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Wisp2 Gene Detail
Summary
  • Symbol
    Wisp2
  • Name
    WNT1 inducible signaling pathway protein 2
  • Synonyms
    CCN5, Crgr4, rCop1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328326
    NCBI Gene: 22403
Location & Maps
more
  • Sequence Map
    Chr2:163820861-163833146 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12286 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 84.49 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    WISP2, WNT1 inducible signaling pathway protein 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    WISP2, WNT1 inducible signaling pathway protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCN5, CT58, CTGF-L
  • Links
    NCBI Gene ID: 8839
    neXtProt AC: NX_O76076

  • Chr Location
    20q13.12; chr20:44714993-44727812 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001174 VEGA Gene Model | MGI Sequence Detail 12286 C57BL/6J ±  kb
transcript OTTMUST00000002301 VEGA | MGI Sequence Detail 1719 Not Applicable  
polypeptide OTTMUSP00000001131 VEGA | MGI Sequence Detail 251 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    153 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000017427 WNT1-inducible-signaling pathway protein 2
  • InterPro Domains
    IPR009030 Growth factor receptor cysteine-rich domain
    IPR000867 Insulin-like growth factor-binding protein, IGFBP
    IPR017891 Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
    IPR000884 Thrombospondin type-1 (TSP1) repeat
    IPR001007 VWFC domain
Molecular
Reagents
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  • All nucleic 16
    cDNA 13
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1354167
References
more
  • Summaries
    All 37
    Developmental Gene Expression 8
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:50091 Zhang R, et al., Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation. Mol Cell Biol. 1998 Oct;18(10):6131-41
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory