Syngr1
Gene Detail

Symbol

Name
ID

Syngr1
synaptogyrin 1
MGI:1328323

Synonyms

p29, Syngr1b

Feature Type

protein coding gene

Genetic Map

Chromosome 15
37.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr15:80091334-80119501 bp, + strand From VEGA annotation of GRCm38   28168 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:3456  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: synaptogyrin
Gene Tree: Syngr1

Human
homologs

Human Homolog		SYNGR1, synaptogyrin 1
NCBI Gene ID		9145
neXtProt AC		NX_O43759
Human Chr (Location)		22q13.1; chr22:39349949-39385588 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(69) : Gene trapped(65) Radiation induced(1) Targeted(3)
Genomic Mutations involving Syngr1 (1)
 

Mice homozygous for a knock-out allele exhibit a moderate decrease in post-tetanic potentiation.

 
Phenotype Images(2)

Interactions

Syngr1 interacts with 283 markers (Mir10a, Mir10b, Mir15b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (13 annotations)

Process	protein targeting, regulation of long-term neuronal synaptic plasticity, ...
Component	cell junction, integral component of membrane, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (98)    Tissues (49)    Images (2)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	90
Northern blot	8

cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(20) cDNA(17) Other(3)
Microarray probesets(7)

Other database
links

VEGA Gene Model	OTTMUSG00000016389 (Evidence)
Ensembl Gene Model	ENSMUSG00000022415 (Evidence)
Entrez Gene	20972 (Evidence)
DFCI	TC1587342, TC1597698, TC1577475, TC1759575, TC1655125
DoTS	DT.110824888, DT.110824906, DT.529515, DT.110824956, DT.110824920, DT.94139623, DT.91375445, DT.97369136, DT.99859616
NIA Mouse Gene Index	U016441
Consensus CDS Project	CCDS27657.1, CCDS27658.1
International Mouse Knockout Project Status	Syngr1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016389	VEGA Gene Model | MGI Sequence Detail	28168	C57BL/6J
transcript	OTTMUST00000039471	VEGA | MGI Sequence Detail	4180	Not Applicable
polypeptide	OTTMUSP00000017634	VEGA | MGI Sequence Detail	234	Not Applicable

All sequences(69) RefSeq(6) UniProt(4)

Polymorphisms

SNPs within 2kb(176 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR008253	Marvel
InterPro	IPR016579	Synaptogyrin
Protein Ontology	PR:000015878	synaptogyrin-1

References

(Earliest) J:50126 Kedra D, et al., Characterization of the human synaptogyrin gene family. Hum Genet. 1998 Aug;103(2):131-41
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)

Other
accession IDs

MGI:2146324