About   Help   FAQ
Syngr1 Gene Detail
Summary
  • Symbol
    Syngr1
  • Name
    synaptogyrin 1
  • Synonyms
    p29, Syngr1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328323
    NCBI Gene: 20972
  • Gene Overview
    MyGene.info: SYNGR1
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr15:80091334-80119501 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      28168 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.85 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SYNGR1, synaptogyrin 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SYNGR1, synaptogyrin 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 9145
    neXtProt AC: NX_O43759
    UniProt: O43759

  • Chr Location
    22q13.1; chr22:39349949-39385588 (+)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    28 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    71
  • Chemically induced (other)
    1
  • Gene trapped
    65
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Syngr1
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    33 strains or lines available
Mice homozygous for a knock-out allele exhibit a moderate decrease in post-tetanic potentiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    98
  • Tissues
    49
  • cDNA Data
    16
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016389 VEGA Gene Model | MGI Sequence Detail 28168 C57BL/6J ±  kb
transcript OTTMUST00000039471 VEGA | MGI Sequence Detail 4180 Not Applicable  
polypeptide OTTMUSP00000017634 VEGA | MGI Sequence Detail 234 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    175 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 17
    Other 3

    Microarray probesets 7
Other
Accession IDs
less
MGI:2146324
References
more
  • Summaries
    All 57
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 7
    Phenotypes 28
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
04/17/2018
MGI 6.11 		The Jackson Laboratory