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Bex1 Gene Detail
Summary
  • Symbol
    Bex1
  • Name
    brain expressed X-linked 1
  • Synonyms
    Rex3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328321
    NCBI Gene: 19716
  • Gene Overview
    MyGene.info: BEX2
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:136213972-136215513 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 57.40 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    22 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328321
protein coding gene ChrX:136213972-136215513 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036095
protein coding gene ChrX:133584329-133586329 (-)
A/J MGP_AJ_G0036076
protein coding gene ChrX:132981494-132982969 (-)
AKR/J MGP_AKRJ_G0036002
protein coding gene ChrX:137251392-137252867 (-)
BALB/cJ MGP_BALBcJ_G0036064
protein coding gene ChrX:131367980-131369521 (-)
C3H/HeJ MGP_C3HHeJ_G0035775
protein coding gene ChrX:133570045-133571034 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036588
protein coding gene ChrX:137422744-137425887 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033419
protein coding gene ChrX:124973767-124975242 (-)
CAST/EiJ MGP_CASTEiJ_G0035064
protein coding gene ChrX:114504694-114662388 (-)
CBA/J MGP_CBAJ_G0035750
protein coding gene ChrX:141647597-141648586 (-)
DBA/2J MGP_DBA2J_G0035906
protein coding gene ChrX:132319056-132320597 (-)
FVB/NJ MGP_FVBNJ_G0035841
protein coding gene ChrX:131499401-131500396 (-)
LP/J MGP_LPJ_G0036001
protein coding gene ChrX:134507771-134508765 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035876
protein coding gene ChrX:149037452-149038447 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036626
protein coding gene ChrX:132935834-132936829 (-)
PWK/PhJ MGP_PWKPhJ_G0034756
protein coding gene ChrX:111403962-111406928 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034586
protein coding gene ChrX:115136375-115139222 (-)
WSB/EiJ MGP_WSBEiJ_G0035197
protein coding gene ChrX:131271058-131272635 (-)



Homology
more
  • Human Ortholog
    BEX2, brain expressed X-linked 2
  • Vertebrate Orthologs
    3
  • Human Ortholog
    BEX2, brain expressed X-linked 2
    Orthology source: HGNC
  • Synonyms
    BEX1, DJ79P11.1
  • Links
    NCBI Gene ID: 84707
    neXtProt AC: NX_Q9BXY8
    UniProt: Q9BXY8

  • Chr Location
    Xq22.2; chrX:103309346-103311046 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele display impaired exercise performance and abnormal muscle regeneration.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19716 NCBI Gene Model | MGI Sequence Detail 1542 C57BL/6J ±  kb
transcript NM_009052 RefSeq | MGI Sequence Detail 890 Not Specified  
polypeptide Q9R224 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007623 Brain-expressed X-linked protein
    IPR021156 Transcription elongation factor A-like/Brain expressed X-linked
Molecular
Reagents
less
  • All nucleic 60
    cDNA 56
    Primer pair 4

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147819, MGI:2147956
References
more
  • Summaries
    All 42
    Developmental Gene Expression 12
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:50125 Faria TN, et al., Characterization of genes which exhibit reduced expression during the retinoic acid-induced differentiation of F9 teratocarcinoma cells: involvement of cyclin D3 in RA-mediated growth arrest. Mol Cell Endocrinol. 1998 Aug 25;143(1-2):155-66
  • Latest
    J:257186 Accornero F, et al., BEX1 is an RNA-dependent mediator of cardiomyopathy. Nat Commun. 2017 Nov 30;8(1):1875

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory