Atp6v0e MGI Mouse Gene Detail - MGI:1328318 - ATPase, H+ transporting, lysosomal V0 subunit E

Atp6v0e Gene Detail

Human Ortholog

ATP6V0E1, ATPase H+ transporting V0 subunit e1
Orthology source: HomoloGene, HGNC
Synonyms

ATP6H, ATP6V0E, M9.2, Vma21, Vma21p
Links

HGNC:863

NCBI Gene ID: 8992

neXtProt AC: NX_O15342

UniProt: O15342
Chr Location

5q35.1; chr5:172983760-173034897 (+) GRCh38.p7

HomoloGene

Vertebrate Homology Class 2931
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
HCOP

human homology predictions: ATP6V0E1
Protein SuperFamily

V-type ATPase, subunits e1/e2
Gene Tree

Atp6v0e

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Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

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			Length	Strain/Species	Flank
genomic	ENSMUSG00000015575	Ensembl Gene Model \| MGI Sequence Detail	23249	C57BL/6J	± kb
transcript	ENSMUST00000015719	Ensembl \| MGI Sequence Detail	794	Not Applicable
polypeptide	ENSMUSP00000015719	Ensembl \| MGI Sequence Detail	81	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000004478 V-type proton ATPase subunit e 1

(term hierarchy)
InterPro Domains

IPR008389 ATPase, V0 complex, subunit e1/e2

IPR017385 ATPase, V0 complex, subunit e1/e2, metazoa

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Summaries

All 32

Developmental Gene Expression 3

Gene Ontology 5

Phenotypes 7
Earliest

J:47435 Ludwig J, et al., Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules. J Biol Chem. 1998 May 1;273(18):10939-47
Latest

J:194116 Flachs P, et al., Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet. 2012;8(11):e1003044

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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