About   Help   FAQ
Cd83
Gene Detail
 Symbol
Name
ID
Cd83
CD83 antigen
MGI:1328316
Feature Type protein coding gene
Genetic Map
Chromosome 13
21.60 cM, cytoband A4-5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:43785107-43803130 bp, + strand
From Ensembl annotation of GRCm38

  18024 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3121  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Cd83

Human
homologs
Human Homolog CD83, CD83 molecule
NCBI Gene ID 9308
neXtProt AC  NX_Q01151
Human Synonyms  BL11, HB15
Human Chr (Location)  6p23; chr6:14117256-14136918 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Chemically induced (ENU)(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice lacking this gene develop, thrive, and reproduce normally, but exhibit defects in T cell development.
 
Interactions
Cd83 interacts with 209 markers (Mir1b, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process negative regulation of interleukin-4 production, positive regulation of CD4-positive, alpha-beta T cell differentiation, ...
Component external side of plasma membrane, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (23)    Tissues (21)    Images (2)
Theiler Stages: 17, 20, 28
Assay TypeResults
RNA in situ 23
cDNA source data(40)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(44) Genomic(3) cDNA(40) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000015396 (Evidence)
Entrez Gene12522 (Evidence)
UniGene57175
DFCITC1571999, TC1700288
DoTSDT.489324, DT.99864765
NIA Mouse Gene IndexU014778
Consensus CDS ProjectCCDS26481.1
International Mouse Knockout Project StatusCd83
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015396 Ensembl Gene Model | MGI Sequence Detail 18024 C57BL/6J ±  kb
transcript ENSMUST00000015540 Ensembl | MGI Sequence Detail 2143 Not Applicable 
polypeptide ENSMUSP00000015540 Ensembl | MGI Sequence Detail 196 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(2)
Polymorphisms PCR(1) : SNPs within 2kb(141 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000001310 CD83 molecule
References (Earliest) J:51033 Twist CJ, et al., The mouse Cd83 gene: structure, domain organization, and chromosome localization. Immunogenetics. 1998 Nov-Dec;48(6):383-93
(Latest) J:200519 Uhde M, et al., Differential regulation of marginal zone and follicular B cell responses by CD83. Int Immunol. 2013 Sep;25(9):507-20
All references(43)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory