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Cd83
Gene Detail
Symbol

Name
ID
Cd83
CD83 antigen
MGI:1328316
Feature Type
protein coding gene
Genetic Map
Chromosome 13
21.60 cM, cytoband A4-5
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:43785112-43803133 bp, + strand
From NCBI annotation of GRCm38

  18022 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3121  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: CD83
Gene Tree: Cd83

Human
homologs
CD83, CD83 molecule
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9308
neXtProt AC: NX_Q01151

Human Synonyms: BL11, HB15

Human Chr (Location): 6p23; chr6:14117256-14136918 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Chemically induced (ENU)(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice lacking this gene develop, thrive, and reproduce normally, but exhibit defects in T cell development.
 
Interactions
Cd83 interacts with 209 markers (Mir1b, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (24)    Tissues (22)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 23
RT-PCR 1
cDNA source data(40)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) Genomic(3) cDNA(40) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000015396 (Evidence)
Entrez Gene 12522 (Evidence)
UniGene 57175
DFCI TC1571999, TC1700288
DoTS DT.99864765, DT.489324
NIA Mouse Gene Index U014778
Consensus CDS Project CCDS26481.1
International Mouse Phenotyping Consortium Status Cd83
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12522 NCBI Gene Model | MGI Sequence Detail 18022 C57BL/6J ±  kb
transcript NM_009856 RefSeq | MGI Sequence Detail 2141 C57BL/6 
polypeptide O88324 UniProt | EBI | MGI Sequence Detail 196 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(2)
Polymorphisms
PCR(1) : SNPs within 2kb(141 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000001310 CD83 molecule
Graphical View of Protein Domain Structure
References
(Earliest) J:51033 Twist CJ, et al., The mouse Cd83 gene: structure, domain organization, and chromosome localization. Immunogenetics. 1998 Nov-Dec;48(6):383-93
(Latest) J:200519 Uhde M, et al., Differential regulation of marginal zone and follicular B cell responses by CD83. Int Immunol. 2013 Sep;25(9):507-20
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory