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Scrg1 Gene Detail
Summary
  • Symbol
    Scrg1
  • Name
    scrapie responsive gene 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328308
    NCBI Gene: 20284
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:57455923-57477585 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 29.80 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328308
protein coding gene Chr8:57455880-57479360 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033622
protein coding gene Chr8:57180088-57206311 (+)
A/J MGP_AJ_G0033604
protein coding gene Chr8:54769979-54791522 (+)
AKR/J MGP_AKRJ_G0033529
protein coding gene Chr8:56396644-56419550 (+)
BALB/cJ MGP_BALBcJ_G0033601
protein coding gene Chr8:55090971-55114634 (+)
C3H/HeJ MGP_C3HHeJ_G0033310
protein coding gene Chr8:57054149-57076006 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034117
protein coding gene Chr8:59384786-59409886 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031065
protein coding gene Chr8:50319916-50342550 (+)
CAST/EiJ MGP_CASTEiJ_G0032636
protein coding gene Chr8:56433680-56465908 (+)
CBA/J MGP_CBAJ_G0033289
protein coding gene Chr8:61501250-61525595 (+)
DBA/2J MGP_DBA2J_G0033442
protein coding gene Chr8:54578058-54599653 (+)
FVB/NJ MGP_FVBNJ_G0033383
protein coding gene Chr8:53936853-53958462 (+)
LP/J MGP_LPJ_G0033530
protein coding gene Chr8:57190805-57213479 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033427
protein coding gene Chr8:63113130-63138098 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034135
protein coding gene Chr8:56627832-56653505 (+)
PWK/PhJ MGP_PWKPhJ_G0032344
protein coding gene Chr8:53889646-53912073 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032180
protein coding gene Chr8:55497882-55521204 (+)
WSB/EiJ MGP_WSBEiJ_G0032752
protein coding gene Chr8:56882653-56905999 (+)



Homology
more
  • Human Ortholog
    SCRG1, stimulator of chondrogenesis 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SCRG1, stimulator of chondrogenesis 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SCRG-1
  • Links
    NCBI Gene ID: 11341
    neXtProt AC: NX_O75711
    UniProt: O75711

  • Chr Location
    4q34.1; chr4:173388148-173486378 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    5
  • Genomic Mutations
    1 involving Scrg1
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031610 Ensembl Gene Model | MGI Sequence Detail 21663 C57BL/6J ±  kb
transcript ENSMUST00000034023 Ensembl | MGI Sequence Detail 700 Not Applicable  
polypeptide ENSMUSP00000034023 Ensembl | MGI Sequence Detail 98 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    Genomic 2
    cDNA 8
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142768
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:47094 Dandoy-Dron F, et al., Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J Biol Chem. 1998 Mar 27;273(13):7691-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory