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Scrg1 Gene Detail
Summary
  • Symbol
    Scrg1
  • Name
    scrapie responsive gene 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328308
    NCBI Gene: 20284
Location & Maps
more
  • Sequence Map
    Chr8:57455923-57477585 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21663 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 29.80 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    SCRG1, stimulator of chondrogenesis 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SCRG1, stimulator of chondrogenesis 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SCRG-1
  • Links
    NCBI Gene ID: 11341
    neXtProt AC: NX_O75711

  • Chr Location
    4q34.1; chr4:173388148-173476691 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    5
  • Genomic Mutations
    1 involving Scrg1
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000060715 VEGA Gene Model | MGI Sequence Detail 21663 C57BL/6J ±  kb
transcript OTTMUST00000148434 VEGA | MGI Sequence Detail 700 Not Applicable  
polypeptide OTTMUSP00000077167 VEGA | MGI Sequence Detail 98 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    141 from dbSNP Build 142
  • PCR
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014536 scrapie-responsive protein 1
  • InterPro Domains
    IPR028063 Scrapie-responsive protein 1
Molecular
Reagents
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  • All nucleic 10
    Genomic 2
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:2142768
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:47094 Dandoy-Dron F, et al., Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J Biol Chem. 1998 Mar 27;273(13):7691-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory