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Gspt1 Gene Detail
Summary
  • Symbol
    Gspt1
  • Name
    G1 to S phase transition 1
  • Synonyms
    G1st, Gst-1, Gst-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1316728
    NCBI Gene: 14852
  • Gene Overview
    MyGene.info: GSPT1
Location & Maps
more
  • Sequence Map
    Chr16:11219292-11254270 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34979 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 6.38 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    GSPT1, G1 to S phase transition 1
  • Vertebrate Orthologs
    12
  • Human Ortholog
    GSPT1, G1 to S phase transition 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    551G9.2, eRF3a, ETF3A, GST1
  • Links
    NCBI Gene ID: 2935
    neXtProt AC: NX_P15170

  • Chr Location
    16p13.1; chr16:11868128-11916662 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 68226
    1 human;1 mouse;2 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: GSPT1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035233 VEGA Gene Model | MGI Sequence Detail 34979 C57BL/6J ±  kb
transcript OTTMUST00000089812 VEGA | MGI Sequence Detail 2898 Not Applicable  
polypeptide OTTMUSP00000049118 VEGA | MGI Sequence Detail 636 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    145 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000008290 eukaryotic peptide chain release factor GTP-binding subunit ERF3A
  • PDB
  • InterPro Domains
    IPR009818 Ataxin-2, C-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR005225 Small GTP-binding protein domain
    IPR000795 Transcription factor, GTP-binding domain
    IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
    IPR004160 Translation elongation factor EFTu/EF1A, C-terminal
    IPR004161 Translation elongation factor EFTu/EF1A, domain 2
    IPR009000 Translation protein, beta-barrel domain
    IPR031157 Tr-type G domain, conserved site
Molecular
Reagents
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  • All nucleic 24
    cDNA 24

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-10304, MGD-MRK-9913, MGI:2146405, MGI:2146418, MGI:2146605, MGI:2146705, MGI:95605
References
more
  • Summaries
    All 36
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:10106 Hoshino S, et al., A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells. EMBO J. 1989 Dec 1;8(12):3807-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory