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Gspt2 Gene Detail
Summary
  • Symbol
    Gspt2
  • Name
    G1 to S phase transition 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1316727
    NCBI Gene: 14853
  • Gene Overview
    MyGene.info: GSPT2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:94636069-94638562 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 41.63 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    19 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1316727
protein coding gene ChrX:94636069-94643244 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035913
protein coding gene ChrX:91062105-91069280 (+)
A/J MGP_AJ_G0035899
protein coding gene ChrX:91142410-91150660 (+)
AKR/J MGP_AKRJ_G0035816
protein coding gene ChrX:93552475-93559656 (+)
BALB/cJ MGP_BALBcJ_G0035883
protein coding gene ChrX:89864541-89871722 (+)
C3H/HeJ MGP_C3HHeJ_G0035592
protein coding gene ChrX:91416496-91423677 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036412
protein coding gene ChrX:93840837-93848012 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033239
protein coding gene ChrX:89283153-89290411 (+)
CAST/EiJ MGP_CASTEiJ_G0034877
protein coding gene ChrX:76079226-76086458 (+)
CBA/J MGP_CBAJ_G0035566
protein coding gene ChrX:96542672-96549853 (+)
DBA/2J MGP_DBA2J_G0035722
protein coding gene ChrX:90367183-90374307 (+)
FVB/NJ MGP_FVBNJ_G0035661
protein coding gene ChrX:89777552-89784704 (+)
LP/J MGP_LPJ_G0035811
protein coding gene ChrX:91876906-91884081 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035695
protein coding gene ChrX:100899425-100906600 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036439
protein coding gene ChrX:90762437-90769618 (+)
PWK/PhJ MGP_PWKPhJ_G0034576
protein coding gene ChrX:73844027-73851325 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034406
protein coding gene ChrX:76941894-76949088 (+)
WSB/EiJ MGP_WSBEiJ_G0035018
protein coding gene ChrX:89568774-89575955 (+)



Homology
more
  • Human Ortholog
    GSPT2, G1 to S phase transition 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    GSPT2, G1 to S phase transition 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ERF3B, GST2
  • Links
    NCBI Gene ID: 23708
    neXtProt AC: NX_Q8IYD1
    UniProt: Q8IYD1

  • Chr Location
    Xp11.22; chrX:51743385-51746232 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14853 NCBI Gene Model | MGI Sequence Detail 2494 C57BL/6J ±  kb
transcript NM_008179 RefSeq | MGI Sequence Detail 2508 C57BL/6  
polypeptide Q149F3 UniProt | EBI | MGI Sequence Detail 632 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008291 eukaryotic peptide chain release factor GTP-binding subunit ERF3B
  • InterPro Domains
    IPR009818 Ataxin-2, C-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR000795 Transcription factor, GTP-binding domain
    IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
    IPR004160 Translation elongation factor EFTu/EF1A, C-terminal
    IPR004161 Translation elongation factor EFTu-like, domain 2
    IPR009000 Translation protein, beta-barrel domain superfamily
    IPR031157 Tr-type G domain, conserved site
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:49569 Hoshino S, et al., Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1. J Biol Chem. 1998 Aug 28;273(35):22254-9
  • Latest
    J:215468 Li X, et al., Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton. Mol Cell. 2014 Jul 17;55(2):305-18

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory