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St3gal3
Gene Detail
Symbol

Name
ID
St3gal3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
MGI:1316659
Synonyms
Siat3, Siat6, ST3Gal III
Feature Type
protein coding gene
Genetic Map
Chromosome 4
53.84 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:117932154-118134914 bp, - strand
From VEGA annotation of GRCm38

  202761 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7539  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: sialyltransferase
Gene Tree: St3gal3

Human
homologs
Human Homolog ST3GAL3, ST3 beta-galactoside alpha-2,3-sialyltransferase 3
NCBI Gene ID 6487
neXtProt AC  NX_Q11203
Human Synonyms  EIEE15, MRT12, SIAT6, ST3GALII, ST3GalIII, ST3N
Human Chr (Location)  1p34.1; chr1:43707533-43931165 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(11) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene show an apparently normal phenotype.
 
Interactions
St3gal3 interacts with 149 markers (Mir7-2, Mir7b, Mir10a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (136)    Tissues (115)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 27
RT-PCR 15
cDNA source data(39)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(42) cDNA(40) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000008662 (Evidence)
Ensembl Gene ModelENSMUSG00000028538 (Evidence)
Entrez Gene20441 (Evidence)
UniGene251002
DFCITC1580244, TC1596553, TC1609535
DoTSDT.101366159, DT.490356, DT.55276342
NIA Mouse Gene IndexU025441
EC2.4.99.6
Consensus CDS ProjectCCDS18544.1, CCDS71458.1
International Mouse Knockout Project StatusSt3gal3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008662 VEGA Gene Model | MGI Sequence Detail 202761 C57BL/6J ±  kb
transcript OTTMUST00000019635 VEGA | MGI Sequence Detail 2549 Not Applicable 
polypeptide OTTMUSP00000008999 VEGA | MGI Sequence Detail 374 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(34) UniProt(6)
Polymorphisms
SNPs within 2kb(2032 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2036)
Protein-related
information
ResourceIDDescription
InterPro IPR001675 Glycosyl transferase, family 29
InterPro IPR012163 Sialyltransferase
Protein Ontology PR:000015681 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
References
(Earliest) J:41275 Kono M, et al., Mouse beta-galactoside alpha 2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression. Glycobiology. 1997 Jun;7(4):469-79
(Latest) J:204846 Suzukawa M, et al., Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice. J Immunol. 2013 Jun 15;190(12):5939-48
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory