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Ahnak Gene Detail
Summary
  • Symbol
    Ahnak
  • Name
    AHNAK nucleoprotein (desmoyokin)
  • Synonyms
    1110004P15Rik, 2310047C17Rik, DY6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1316648
    NCBI Gene: 66395
  • Gene Overview
    MyGene.info: AHNAK
Location & Maps
more
  • Sequence Map
    Chr19:8989284-9076919 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      87636 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 6.04 cM, cytoband A
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    AHNAK, AHNAK nucleoprotein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AHNAK, AHNAK nucleoprotein
    Orthology source: HomoloGene
  • Synonyms
    AHNAKRS
  • Links
    NCBI Gene ID: 79026
    neXtProt AC: NX_Q09666

  • Chr Location
    11q12.2; chr11:62433542-62546860 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 4 alleles in 4 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069833 Ensembl Gene Model | MGI Sequence Detail 87636 C57BL/6J ±  kb
transcript ENSMUST00000092956 Ensembl | MGI Sequence Detail 18099 Not Applicable  
polypeptide ENSMUSP00000090633 Ensembl | MGI Sequence Detail 5656 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    276 from dbSNP Build 142
Protein
Information
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  • UniProt
    12 Sequences
  • InterPro Domains
    IPR002068 Alpha crystallin/Hsp20 domain
    IPR001478 PDZ domain
Molecular
Reagents
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  • All nucleic 17
    cDNA 16
    Other 1

    Microarray probesets 8
Other
Accession IDs
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MGI:1913645, MGI:1920976, MGI:2147451, MGI:2147673
References
more
  • Summaries
    All 50
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 19
  • Earliest
    J:51303 Hashimoto T, et al., Desmoyokin, a 680 kDa keratinocyte plasma membrane-associated protein, is homologous to the protein encoded by human gene AHNAK. J Cell Sci. 1993 Jun;105(Pt 2):275-86
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory