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Ahnak
Gene Detail
 Symbol
Name
ID
Ahnak
AHNAK nucleoprotein (desmoyokin)
MGI:1316648
Synonyms 1110004P15Rik, 2310047C17Rik, DY6
Feature Type protein coding gene
Genetic Map
Chromosome 19
6.04 cM, cytoband A
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr19:8989284-9076919 bp, + strand
From NCBI annotation of GRCm38

  87636 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:67425  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Ahnak

Human
homologs
Human Homolog AHNAK, AHNAK nucleoprotein
NCBI Gene ID 79026
neXtProt AC  NX_Q09666
Human Synonyms  AHNAKRS
Human Chr (Location)  11q12.2; chr11:62433542-62546860 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(137) : Gene trapped(132) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection.
 
Interactions
Ahnak interacts with 325 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process protein oligomerization, regulation of RNA splicing, ...
Component actin cytoskeleton, cell-cell contact zone, ...
Function poly(A) RNA binding, S100 protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (24)    Tissues (15)    Images (2)
Theiler Stages: 23
Assay TypeResults
RNA in situ 24
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Other(1)
Microarray probesets(8)
Other database
links
Ensembl Gene ModelENSMUSG00000069833 (Evidence)
Entrez Gene66395 (Evidence)
DFCITC1585881, TC1596323, TC1597172, TC1597484, TC1641995, TC1662473
DoTSDT.101400384, DT.110858611, DT.110858623, DT.40143554, DT.535125, DT.94122881
NIA Mouse Gene IndexU168837
Consensus CDS ProjectCCDS29564.1, CCDS50384.1
International Mouse Knockout Project StatusAhnak
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 66395 NCBI Gene Model | MGI Sequence Detail 87636 C57BL/6J ±  kb
transcript NM_009643 RefSeq | MGI Sequence Detail 18100 C57BL/6 
polypeptide NP_033773 RefSeq | MGI Sequence Detail 5656 C57BL/6 

For the selected sequences
All sequences(74) RefSeq(16) UniProt(13)
Polymorphisms SNPs within 2kb(277 from dbSNP Build 137)    SNPs within 2kb including multiple locations(279)
Protein-related
information
ResourceIDDescription
InterPro IPR002068 Alpha crystallin/Hsp20 domain
InterPro IPR001478 PDZ domain
Protein Ontology PR:000003856 neuroblast differentiation-associated protein AHNAK
References (Earliest) J:51303 Hashimoto T, et al., Desmoyokin, a 680 kDa keratinocyte plasma membrane-associated protein, is homologous to the protein encoded by human gene AHNAK. J Cell Sci. 1993 Jun;105(Pt 2):275-86
(Latest) J:211284 von Boxberg Y, et al., Giant scaffolding protein AHNAK1 interacts with beta-dystroglycan and controls motility and mechanical properties of schwann cells. Glia. 2014 Sep;62(9):1392-406
All references(51)
Other
accession IDs
MGI:1913645, MGI:1920976, MGI:2147451, MGI:2147673

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory