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Nrip1
Gene Detail
 Symbol
Name
ID
Nrip1
nuclear receptor interacting protein 1
MGI:1315213
Synonyms 6030458L20Rik, 8430438I05Rik, RIP140
Feature Type protein coding gene
Genetic Map
Chromosome 16
43.65 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:76287400-76373827 bp, - strand
From VEGA annotation of GRCm38

  86428 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2606  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: nuclear receptor-interacting protein 1
Gene Tree: Nrip1

Human
homologs
Human Homolog NRIP1, nuclear receptor interacting protein 1
NCBI Gene ID 8204
neXtProt AC  NX_P48552
Human Synonyms  RIP140
Human Chr (Location)  21q11.2; chr21:14961235-15064929 (-)  GRCh38
Alleles
and
phenotypes
All alleles(159) : Targeted(2) Gene trapped(157)
 
Homozygosity for targeted disruption of this gene results in female infertility due to ovulation failure. Heterozygous females are partially affected. Male and female mice are smaller than wild-type littermates.
 
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process lipid storage, negative regulation of transcription from RNA polymerase II promoter, ...
Component cell junction, histone deacetylase complex, ...
Function estrogen receptor binding, glucocorticoid receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (327)    Tissues (198)    Images (54)
Theiler Stages: 13, 15, 17, 19, 20, 22, 23, 26, 28
Assay TypeResults
RNA in situ 300
Northern blot 9
RT-PCR 18
cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(24) cDNA(21) Primer pair(2) Other(1)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000026674 (Evidence)
Ensembl Gene ModelENSMUSG00000048490 (Evidence)
Entrez Gene268903 (Evidence)
DFCITC1580836, TC1599100, TC1635838
DoTSDT.101219964, DT.102551107, DT.40146258, DT.524225
NIA Mouse Gene IndexU037216
Consensus CDS ProjectCCDS28274.1
International Mouse Knockout Project StatusNrip1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026674 VEGA Gene Model | MGI Sequence Detail 86428 C57BL/6J ±  kb
transcript OTTMUST00000066005 VEGA | MGI Sequence Detail 4529 Not Applicable 
polypeptide OTTMUSP00000032983 VEGA | MGI Sequence Detail 1161 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(12) UniProt(1)
Polymorphisms SNPs within 2kb(523 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026649 Nuclear receptor-interacting protein 1
Protein Ontology PR:000011427 nuclear receptor-interacting protein 1
References (Earliest) J:46180 Katsanis N, et al., Localisation of receptor interacting protein 140 (RIP140) within 100 kb of D21S13 on 21q11, a gene-poor region of the human genome. Hum Genet. 1998 Feb;102(2):221-3
(Latest) J:196080 Elsen GE, et al., The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
All references(76)
Other
accession IDs
MGI:1918801, MGI:1925132, MGI:2146368, MGI:2146638

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory