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Grcc10 Gene Detail
Summary
  • Symbol
    Grcc10
  • Name
    gene rich cluster, C10 gene
  • Synonyms
    2310033H05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1315201
    NCBI Gene: 14790
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124739183-124741079 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1315201
protein coding gene Chr6:124739183-124741374 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031263
protein coding gene Chr6:128043809-128046004 (-)
A/J MGP_AJ_G0031233
protein coding gene Chr6:123230227-123232413 (-)
AKR/J MGP_AKRJ_G0031161
protein coding gene Chr6:126588800-126590989 (-)
BALB/cJ MGP_BALBcJ_G0031241
protein coding gene Chr6:122830083-122832271 (-)
C3H/HeJ MGP_C3HHeJ_G0030964
protein coding gene Chr6:126639812-126642000 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031697
protein coding gene Chr6:131432792-131435025 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028847
protein coding gene Chr6:120416842-120419036 (-)
CAST/EiJ MGP_CASTEiJ_G0030345
protein coding gene Chr6:126842030-126844221 (-)
CBA/J MGP_CBAJ_G0030925
protein coding gene Chr6:136462236-136464422 (-)
DBA/2J MGP_DBA2J_G0031081
protein coding gene Chr6:122155824-122158013 (-)
FVB/NJ MGP_FVBNJ_G0031031
protein coding gene Chr6:121059796-121061989 (-)
LP/J MGP_LPJ_G0031161
protein coding gene Chr6:128217810-128220000 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031069
protein coding gene Chr6:140514274-140516460 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031732
protein coding gene Chr6:126480470-126482659 (-)
PWK/PhJ MGP_PWKPhJ_G0030060
protein coding gene Chr6:120383835-120386015 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029889
protein coding gene Chr6:124556629-124558808 (-)
WSB/EiJ MGP_WSBEiJ_G0030430
protein coding gene Chr6:126839980-126842167 (-)



Homology
more
  • Human Ortholog
    C12orf57, chromosome 12 open reading frame 57
  • Vertebrate Orthologs
    9
  • Human Ortholog
    C12orf57, chromosome 12 open reading frame 57
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10, GRCC10
  • Links
    NCBI Gene ID: 113246
    neXtProt AC: NX_Q99622
    UniProt: Q99622

  • Chr Location
    12p13.31; chr12:6943438-6946003 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14790 NCBI Gene Model | MGI Sequence Detail 1897 C57BL/6J ±  kb
    transcript NM_013535 RefSeq | MGI Sequence Detail 572 C57BL/6  
    polypeptide O35127 UniProt | EBI | MGI Sequence Detail 126 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 124
      Genomic 1
      cDNA 123

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1923999
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:45711 Ansari-Lari MA, et al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res. 1998 Jan;8(1):29-40
    • Latest
      J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    03/19/2019
    MGI 6.13
    The Jackson Laboratory