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Cdca3 Gene Detail
Summary
  • Symbol
    Cdca3
  • Name
    cell division cycle associated 3
  • Synonyms
    2410005A12Rik, Grcc8, TOME-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1315198
    NCBI Gene: 14793
  • Gene Overview
    MyGene.info: CDCA3
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124829547-124833701 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1315198
 protein coding gene Chr6:124829506-124833701 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031271
 protein coding gene Chr6:128136334-128140488 (+)
A/J MGP_AJ_G0031241
 protein coding gene Chr6:123315824-123319980 (+)
AKR/J MGP_AKRJ_G0031169
 protein coding gene Chr6:126681010-126685157 (+)
BALB/cJ MGP_BALBcJ_G0031249
 protein coding gene Chr6:122915498-122919849 (+)
C3H/HeJ MGP_C3HHeJ_G0030972
 protein coding gene Chr6:126728151-126732304 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031705
 protein coding gene Chr6:131519924-131524059 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028855
 protein coding gene Chr6:120526042-120530211 (+)
CAST/EiJ MGP_CASTEiJ_G0030353
 protein coding gene Chr6:126931911-126936808 (+)
CBA/J MGP_CBAJ_G0030933
 protein coding gene Chr6:136551460-136555614 (+)
DBA/2J MGP_DBA2J_G0031089
 protein coding gene Chr6:122242356-122246499 (+)
FVB/NJ MGP_FVBNJ_G0031039
 protein coding gene Chr6:121144665-121149275 (+)
LP/J MGP_LPJ_G0031169
 protein coding gene Chr6:128307123-128311265 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031077
 protein coding gene Chr6:140610635-140614983 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031740
 protein coding gene Chr6:126573905-126578052 (+)
PWK/PhJ MGP_PWKPhJ_G0030068
 protein coding gene Chr6:120473176-120477331 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029897
 protein coding gene Chr6:124657143-124662710 (+)
WSB/EiJ MGP_WSBEiJ_G0030438
 protein coding gene Chr6:126932882-126938469 (+)



Homology
more
  • Human Ortholog
    CDCA3, cell division cycle associated 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CDCA3, cell division cycle associated 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GRCC8, TOME-1
  • Links
    NCBI Gene ID: 83461
    neXtProt AC: NX_Q99618
    UniProt: Q99618

  • Chr Location
    12p13.31; chr12:6844796-6852066 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 8403
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CDCA3
  • Gene Tree
    Cdca3
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotypes from multigenic genotypes
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    166
  • Tissues
    18
  • cDNA Data
    145
  • Literature Summary
    6
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023505 Ensembl Gene Model | MGI Sequence Detail 4155 C57BL/6J ±  kb
transcript ENSMUST00000024270 Ensembl | MGI Sequence Detail 1976 Not Applicable  
polypeptide ENSMUSP00000024270 Ensembl | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 146
    Genomic 1
    cDNA 145

    Microarray probesets 5
Other
Accession IDs
less
MGI:1913551
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:45711 Ansari-Lari MA, et al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res. 1998 Jan;8(1):29-40
  • Latest
    J:267889 Moon S, et al., Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/15/2019
MGI 6.14 		The Jackson Laboratory