Cdca3 Gene Detail

Summary

• Symbol
  Cdca3
• Name
  cell division cycle associated 3
• Synonyms
  2410005A12Rik, Grcc8, TOME-1

• Feature Type
  protein coding gene
• IDs
  MGI:1315198
  NCBI Gene: 14793
• Gene Overview
  MyGene.info: CDCA3

Location & Maps

• Sequence Map
  Chr6:124829547-124833701 bp, + strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    4155 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 59.17 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  CDCA3, cell division cycle associated 3

• Vertebrate Orthologs
  9

• Human Ortholog
  CDCA3, cell division cycle associated 3
  Orthology source: HomoloGene, HGNC
• Synonyms
  GRCC8, TOME-1
• Links
  HGNC:14624

  NCBI Gene ID: 83461

  neXtProt AC: NX_Q99618

  UniProt: Q99618

  
  
• Chr Location
  12p13.31; chr12:6844796-6852066 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 8403
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: CDCA3
• Gene Tree
  Cdca3
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  21
• Gene trapped
  18
• Targeted
  3
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  14 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  4
• GO References
  2

• External Resources
  FuncBase

Expression

• Assay Results
  166
• Tissues
  18
• cDNA Data
  144
• Literature Summary
  4

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  GEISHA CDCA3
  Xenbase cdca3

Interactions

• Cdca3 interacts with 117 markers (Mir9-1, Mir9-2, Mir9-3, ...) View All

Sequences &
Gene Models

• All Sequences
  48
• RefSeq
  6
• UniProt
  4
• CCDS
  CCDS39629.1
• UniGene
  285723

• VEGA
  OTTMUSG00000024338 (Evidence)
• Ensembl
  ENSMUSG00000023505 (Evidence)
• NCBI Gene
  14793

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000024338	VEGA Gene Model | MGI Sequence Detail	4155	C57BL/6J
transcript	OTTMUST00000059621	VEGA | MGI Sequence Detail	1976	Not Applicable
polypeptide	OTTMUSP00000029014	VEGA | MGI Sequence Detail	266	Not Applicable

Polymorphisms

• SNPs within 2kb
  4 from dbSNP Build 142

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000005221 cell division cycle-associated protein 3
  (term hierarchy)

Molecular
Reagents

• All nucleic 145

  Genomic 1

  cDNA 144

  
  

  Microarray probesets 5

Other
Accession IDs

MGI:1913551

References

• Summaries
  All 37

  Developmental Gene Expression 4

  Gene Ontology 2

  Phenotypes 7
• Earliest
  J:45711 Ansari-Lari MA, et al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res. 1998 Jan;8(1):29-40
• Latest
  J:233777 Ray JP, et al., The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. 2015 Oct 20;43(4):690-702