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Cdca3 Gene Detail
Summary
  • Symbol
    Cdca3
  • Name
    cell division cycle associated 3
  • Synonyms
    2410005A12Rik, Grcc8, TOME-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1315198
    NCBI Gene: 14793
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124806533-124810664 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    163 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1315198
 protein coding gene Chr6:124806510-124810664 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031271
 protein coding gene Chr6:128136334-128140488 (+)
A/J MGP_AJ_G0031241
 protein coding gene Chr6:123315824-123319980 (+)
AKR/J MGP_AKRJ_G0031169
 protein coding gene Chr6:126681010-126685157 (+)
BALB/cJ MGP_BALBcJ_G0031249
 protein coding gene Chr6:122915498-122919849 (+)
C3H/HeJ MGP_C3HHeJ_G0030972
 protein coding gene Chr6:126728151-126732304 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031705
 protein coding gene Chr6:131519924-131524059 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028855
 protein coding gene Chr6:120526042-120530211 (+)
CAST/EiJ MGP_CASTEiJ_G0030353
 protein coding gene Chr6:126931911-126936808 (+)
CBA/J MGP_CBAJ_G0030933
 protein coding gene Chr6:136551460-136555614 (+)
DBA/2J MGP_DBA2J_G0031089
 protein coding gene Chr6:122242356-122246499 (+)
FVB/NJ MGP_FVBNJ_G0031039
 protein coding gene Chr6:121144665-121149275 (+)
LP/J MGP_LPJ_G0031169
 protein coding gene Chr6:128307123-128311265 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031077
 protein coding gene Chr6:140610635-140614983 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031740
 protein coding gene Chr6:126573905-126578052 (+)
PWK/PhJ MGP_PWKPhJ_G0030068
 protein coding gene Chr6:120473176-120477331 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029897
 protein coding gene Chr6:124657143-124662710 (+)
WSB/EiJ MGP_WSBEiJ_G0030438
 protein coding gene Chr6:126932882-126938469 (+)



Homology
more
  • Human Ortholog
    CDCA3, cell division cycle associated 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDCA3, cell division cycle associated 3
  • Synonyms
    GRCC8, TOME-1, TOME1
  • Links
    NCBI Gene ID: 83461
    UniProt: Q99618

  • Chr Location
    12p13.31; chr12:6844793-6851292 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    878
  • Tissues
    23
  • cDNA Data
    146
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14793 NCBI Gene Model | MGI Sequence Detail 4132 C57BL/6J ±  kb
transcript NM_013538 RefSeq | MGI Sequence Detail 1488 ZRU/MplStud  
polypeptide Q99M54 UniProt | EBI | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 147
    Genomic 1
    cDNA 146

    Microarray probesets 5
Other
Accession IDs
less
MGI:1913551
References
more
  • Summaries
    All 41
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:45711 Ansari-Lari MA, et al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res. 1998 Jan;8(1):29-40
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory