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Timm10b Gene Detail
Summary
  • Symbol
    Timm10b
  • Name
    translocase of inner mitochondrial membrane 10B
  • Synonyms
    Fracture Callus 1, FxC1, Tim10b, Tim9b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1315196
    NCBI Gene: 14356
  • Gene Overview
    MyGene.info: TIMM10B
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:105640056-105643637 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 55.93 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    102 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1315196
protein coding gene Chr7:105640056-105656992 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032759
protein coding gene Chr7:108903157-108920131 (+)
A/J MGP_AJ_G0032739
protein coding gene Chr7:106049946-106066105 (+)
AKR/J MGP_AKRJ_G0032672
protein coding gene Chr7:108824099-108839785 (+)
BALB/cJ MGP_BALBcJ_G0032745
protein coding gene Chr7:105766474-105782289 (+)
C3H/HeJ MGP_C3HHeJ_G0032454
protein coding gene Chr7:108931754-108948317 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033250
protein coding gene Chr7:113263402-113282226 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030234
protein coding gene Chr7:108028714-108044596 (+)
CAST/EiJ MGP_CASTEiJ_G0031784
protein coding gene Chr7:100758435-100775237 (+)
CBA/J MGP_CBAJ_G0032428
protein coding gene Chr7:117026875-117047963 (+)
DBA/2J MGP_DBA2J_G0032581
protein coding gene Chr7:104319562-104335384 (+)
FVB/NJ MGP_FVBNJ_G0032534
protein coding gene Chr7:104128570-104144190 (+)
LP/J MGP_LPJ_G0032672
protein coding gene Chr7:110306717-110322292 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032566
protein coding gene Chr7:118613277-118630069 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033271
protein coding gene Chr7:107891324-107908775 (+)
PWK/PhJ MGP_PWKPhJ_G0031497
protein coding gene Chr7:97259762-97277223 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031346
protein coding gene Chr7:95001803-95017233 (+)
WSB/EiJ MGP_WSBEiJ_G0031901
protein coding gene Chr7:108533849-108549381 (+)



Homology
more
  • Human Ortholog
    TIMM10B, translocase of inner mitochondrial membrane 10B
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TIMM10B, translocase of inner mitochondrial membrane 10B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FXC1, TIM10B, Tim9b
  • Links
    NCBI Gene ID: 26515
    neXtProt AC: NX_Q9Y5J6
    UniProt: Q9Y5J6

  • Chr Location
    11p15.4; chr11:6481447-6484681 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Timm10b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000089847 Ensembl Gene Model | MGI Sequence Detail 3582 C57BL/6J ±  kb
transcript ENSMUST00000106784 Ensembl | MGI Sequence Detail 494 Not Applicable  
polypeptide ENSMUSP00000102396 Ensembl | MGI Sequence Detail 102 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 62
    cDNA 62

    Microarray probesets 4
References
more
  • Summaries
    All 40
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory