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Lrrc23 Gene Detail
Summary
  • Symbol
    Lrrc23
  • Name
    leucine rich repeat containing 23
  • Synonyms
    4921537K05Rik, Lrpb7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1315192
    NCBI Gene: 16977
  • Gene Overview
    MyGene.info: LRRC23
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124769863-124779727 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1315192
protein coding gene Chr6:124769863-124780339 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031267
protein coding gene Chr6:128074009-128082960 (-)
A/J MGP_AJ_G0031237
protein coding gene Chr6:123260905-123270580 (-)
AKR/J MGP_AKRJ_G0031165
protein coding gene Chr6:126619481-126629009 (-)
BALB/cJ MGP_BALBcJ_G0031245
protein coding gene Chr6:122860382-122870017 (-)
C3H/HeJ MGP_C3HHeJ_G0030968
protein coding gene Chr6:126670596-126680938 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031701
protein coding gene Chr6:131463560-131473082 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028851
protein coding gene Chr6:120447819-120475591 (-)
CAST/EiJ MGP_CASTEiJ_G0030349
protein coding gene Chr6:126873913-126883355 (-)
CBA/J MGP_CBAJ_G0030929
protein coding gene Chr6:136493685-136503412 (-)
DBA/2J MGP_DBA2J_G0031085
protein coding gene Chr6:122186048-122195807 (-)
FVB/NJ MGP_FVBNJ_G0031035
protein coding gene Chr6:121089953-121100047 (-)
LP/J MGP_LPJ_G0031165
protein coding gene Chr6:128250275-128260559 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031073
protein coding gene Chr6:140547192-140560093 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031736
protein coding gene Chr6:126510744-126523053 (-)
PWK/PhJ MGP_PWKPhJ_G0030064
protein coding gene Chr6:120415216-120425612 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029893
protein coding gene Chr6:124589104-124597338 (-)
WSB/EiJ MGP_WSBEiJ_G0030434
protein coding gene Chr6:126873300-126883577 (-)



Homology
more
  • Human Ortholog
    LRRC23, leucine rich repeat containing 23
  • Vertebrate Orthologs
    11
  • Human Ortholog
    LRRC23, leucine rich repeat containing 23
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LRPB7
  • Links
    NCBI Gene ID: 10233
    neXtProt AC: NX_Q53EV4
    UniProt: Q53EV4

  • Chr Location
    12p13.31; chr12:6904733-6914242 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5082
    1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LRRC23
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030125 Ensembl Gene Model | MGI Sequence Detail 9865 C57BL/6J ±  kb
    transcript ENSMUST00000112475 Ensembl | MGI Sequence Detail 1444 Not Applicable  
    polypeptide ENSMUSP00000108094 Ensembl | MGI Sequence Detail 340 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      Genomic 1
      cDNA 10
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1918196
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:45711 Ansari-Lari MA, et al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res. 1998 Jan;8(1):29-40
    • Latest
      J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory