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Chaf1b Gene Detail
Summary
  • Symbol
    Chaf1b
  • Name
    chromatin assembly factor 1, subunit B (p60)
  • Synonyms
    2600017H24Rik, CAF1, CAF1A, CAF1P60, CAF-1 subunit B, CAF-I 60 kDa subunit, CAF-IP60, MPHOSPH7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1314881
    NCBI Gene: 110749
  • Gene Overview
    MyGene.info: CHAF1B
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:93883901-93906115 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 54.96 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    102 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1314881
protein coding gene Chr16:93883894-93906115 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023065
protein coding gene Chr16:95095066-95118691 (+)
A/J MGP_AJ_G0023033
protein coding gene Chr16:90630788-90652978 (+)
AKR/J MGP_AKRJ_G0023003
protein coding gene Chr16:93411871-93435087 (+)
BALB/cJ MGP_BALBcJ_G0023035
protein coding gene Chr16:91154655-91176900 (+)
C3H/HeJ MGP_C3HHeJ_G0022796
protein coding gene Chr16:93916993-93939872 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023482
protein coding gene Chr16:98110344-98132311 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020984
protein coding gene Chr16:88478410-88501183 (+)
CAST/EiJ MGP_CASTEiJ_G0022315
protein coding gene Chr16:94647158-94669895 (+)
CBA/J MGP_CBAJ_G0022765
protein coding gene Chr16:102359688-102382993 (+)
DBA/2J MGP_DBA2J_G0022899
protein coding gene Chr16:90518449-90540962 (+)
FVB/NJ MGP_FVBNJ_G0022873
protein coding gene Chr16:89675263-89697479 (+)
LP/J MGP_LPJ_G0022969
protein coding gene Chr16:94758849-94781017 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022894
protein coding gene Chr16:106741044-106763173 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023500
protein coding gene Chr16:93912078-93934337 (+)
PWK/PhJ MGP_PWKPhJ_G0022060
protein coding gene Chr16:90768938-90791770 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021890
protein coding gene Chr16:93454460-93475735 (+)
WSB/EiJ MGP_WSBEiJ_G0022366
protein coding gene Chr16:94161064-94185641 (+)



Homology
more
  • Human Ortholog
    CHAF1B, chromatin assembly factor 1 subunit B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHAF1B, chromatin assembly factor 1 subunit B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CAF1, CAF-1, CAF1A, CAF1P60, CAF-IP60, MPHOSPH7, MPP7
  • Links
    NCBI Gene ID: 8208
    neXtProt AC: NX_Q13112
    UniProt: Q13112

  • Chr Location
    21q22.12-q22.13; chr21:36380145-36416827 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 48346
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CHAF1B
  • Gene Tree
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    32 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022945 Ensembl Gene Model | MGI Sequence Detail 22215 C57BL/6J ±  kb
transcript ENSMUST00000023666 Ensembl | MGI Sequence Detail 1922 Not Applicable  
polypeptide ENSMUSP00000023666 Ensembl | MGI Sequence Detail 572 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 2
    cDNA 11
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919322, MGI:2146692
References
more
  • Summaries
    All 63
    Developmental Gene Expression 6
    Diseases 3
    Gene Ontology 5
    Phenotypes 32
  • Earliest
    J:128897 Smith DJ, et al., Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2. Genomics. 1995 Jun 10;27(3):425-34
  • Latest
    J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory