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Chaf1b Gene Detail
Summary
  • Symbol
    Chaf1b
  • Name
    chromatin assembly factor 1, subunit B (p60)
  • Synonyms
    2600017H24Rik, CAF1, CAF1A, CAF1P60, CAF-1 subunit B, CAF-I 60 kDa subunit, CAF-IP60, MPHOSPH7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1314881
    NCBI Gene: 110749
  • Gene Overview
    MyGene.info: CHAF1B
Location & Maps
more
  • Sequence Map
    Chr16:93883901-93906115 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      22215 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 54.96 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    CHAF1B, chromatin assembly factor 1 subunit B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CHAF1B, chromatin assembly factor 1 subunit B
    Orthology source: HomoloGene
  • Synonyms
    CAF1, CAF-1, CAF1A, CAF1P60, CAF-IP60, MPHOSPH7, MPP7
  • Links
    NCBI Gene ID: 8208
    neXtProt AC: NX_Q13112

  • Chr Location
    21q22.13; chr21:36377057-36416827 (+)  GRCh38.p2

Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    25 phenotype references
  • All Mutations and Alleles
    26
  • Gene trapped
    12
  • Targeted
    12
  • Transgenic
    2
  • Genomic Mutations
    8 involving Chaf1b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027288 VEGA Gene Model | MGI Sequence Detail 22215 C57BL/6J ±  kb
transcript OTTMUST00000067449 VEGA | MGI Sequence Detail 1922 Not Applicable  
polypeptide OTTMUSP00000033945 VEGA | MGI Sequence Detail 572 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    102 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000005403 chromatin assembly factor 1 subunit B
  • InterPro Domains
    IPR029129 Chromatin assembly factor 1 subunit B, C-terminal domain
    IPR001632 G-protein, beta subunit
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
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  • All nucleic 14
    Genomic 2
    cDNA 10
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
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MGI:1919322, MGI:2146692
References
more
  • Summaries
    All 34
    Developmental Gene Expression 6
    Diseases 3
    Gene Ontology 4
    Phenotypes 25
  • Earliest
    J:50129 Cabin DE, et al., Physical and comparative mapping of distal mouse chromosome 16. 5 p5. Genome Res. 1998 Sep;8(9):940-50
  • Latest
    J:170314 Albino D, et al., Gene expression profiling identifies eleven DNA repair genes down-regulated during mouse neural crest cell migration. Int J Dev Biol. 2011;55(1):65-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory