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Eif2b3
Gene Detail
Symbol

Name
ID
Eif2b3
eukaryotic translation initiation factor 2B, subunit 3
MGI:1313286
Synonyms
1190002P15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
53.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:117019402-117087306 bp, + strand
From VEGA annotation of GRCm38

  67905 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7005  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: EIF2B3
Gene Tree: Eif2b3

Human
homologs
EIF2B3, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8891
neXtProt AC: NX_Q9NR50

Human Synonyms: EIF-2B, EIF2Bgamma

Human Chr (Location): 1p34.1; chr1:44850522-44986722 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human EIF2B3

Mutations,
alleles, and
phenotypes
All mutations/alleles(150) : Gene trapped(146) Targeted(4)
Genomic Mutations involving Eif2b3 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Eif2b3 interacts with 299 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Expression
Literature Summary: (1 records)
Data Summary: Results (41)    Tissues (28)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 41
cDNA source data(51)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase eif2b3 ; ZFIN eif2b3    NEW 
Molecular
reagents
All nucleic(51) cDNA(51)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000009780 (Evidence)
Ensembl Gene Model ENSMUSG00000028683 (Evidence)
Entrez Gene 108067 (Evidence)
UniGene 34612
DFCI TC1582784, TC1604583, TC1631160, TC1647474, TC1650452
DoTS DT.101349020, DT.50316354, DT.55176237, DT.91284647, DT.91339609, DT.91569053, DT.97369329
NIA Mouse Gene Index U004704
Consensus CDS Project CCDS18524.1, CCDS51279.1
International Mouse Phenotyping Consortium Status Eif2b3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009780 VEGA Gene Model | MGI Sequence Detail 67905 C57BL/6J ±  kb
transcript OTTMUST00000022643 VEGA | MGI Sequence Detail 1555 Not Applicable 
polypeptide OTTMUSP00000010337 VEGA | MGI Sequence Detail 452 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(10) UniProt(6)
Polymorphisms
SNPs within 2kb(447 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR029044 Nucleotide-diphospho-sugar transferases
InterPro IPR005835 Nucleotidyl transferase domain
InterPro IPR011004 Trimeric LpxA-like
Protein Ontology PR:000006964 translation initiation factor eIF-2B subunit gamma
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)
Other
accession IDs
MGI:1916112

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory