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Usp9y
Gene Detail
Symbol

Name
ID
Usp9y
ubiquitin specific peptidase 9, Y chromosome
MGI:1313274
Synonyms
Dffry, Fafl2
Feature Type
protein coding gene
Genetic Map
Chromosome Y
cytoband p

Mapping data(3)
Sequence Map
ChrY:1298961-1459782 bp, - strand
From VEGA annotation of GRCm38

  160822 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68408  Vertebrate Homology Class
1 human; 1 mouse; 1 cattle

Gene Tree: Usp9y

Human
homologs
Human Homolog USP9Y, ubiquitin specific peptidase 9, Y-linked
NCBI Gene ID 8287
neXtProt AC  NX_O00507
Human Synonyms  DFFRY, SPGFY2
Human Chr (Location)  Yq11.2; chrY:12701231-12860843 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human USP9Y
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process proteolysis
Component cellular_component
Function cysteine-type peptidase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (39)    Tissues (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 39
cDNA source data(1)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(6) Genomic(3) cDNA(1) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026255 (Evidence)
Ensembl Gene ModelENSMUSG00000069044 (Evidence)
Entrez Gene107868 (Evidence)
UniGene347376
DoTSDT.94269773
EC3.4.19.12
Consensus CDS ProjectCCDS30544.1
International Mouse Knockout Project StatusUsp9y
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026255 VEGA Gene Model | MGI Sequence Detail 160822 C57BL/6J ±  kb
transcript OTTMUST00000064932 VEGA | MGI Sequence Detail 8094 Not Applicable 
polypeptide OTTMUSP00000032293 VEGA | MGI Sequence Detail 2556 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(4) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(153 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2
InterPro IPR018200 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site
References
(Earliest) J:45388 Brown GM, et al., Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene. Hum Mol Genet. 1998 Jan;7(1):97-107
(Latest) J:204287 Stegeman S, et al., Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFbeta-mediated axonogenesis. PLoS One. 2013;8(7):e68287
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory