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Clip2
Gene Detail
 Symbol
Name
ID
Clip2
CAP-GLY domain containing linker protein 2
MGI:1313136
Synonyms CLIP-115, Cyln2, WSCR4
Feature Type protein coding gene
Genetic Map
Chromosome 5
74.63 cM, cytoband G
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr5:134489386-134552434 bp, - strand
From NCBI annotation of GRCm38

  63049 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20718  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Clip2

Human
homologs
Human Homolog CLIP2, CAP-GLY domain containing linker protein 2
NCBI Gene ID 7461
neXtProt AC  NX_Q9UDT6
Human Synonyms  CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4
Human Chr (Location)  7q11.23; chr7:74289475-74405943 (+)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Targeted(3) Gene trapped(3)
 
Mice homozygous and heterozygous for disruptions in this gene display growth deficiency, brain abnormalities and hippocampal dysfunction and deficits in motor coordination.
 
Human Diseases Modeled Using Mouse Clip2 (1)    Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Component cytoplasm, cytoplasmic microtubule, ...
Function microtubule binding, microtubule plus-end binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (233)    Tissues (46)    Images (24)
Theiler Stages: 15, 17, 19, 20, 22, 23, 24, 28
Assay TypeResults
RNA in situ 201
Northern blot 29
Western blot 3
cDNA source data(94)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(102) Genomic(6) cDNA(95) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000063146 (Evidence)
Entrez Gene269713 (Evidence)
UniGene255138
DFCITC1577891, TC1597342, TC1603551
DoTSDT.101389926, DT.110640831, DT.91324914
NIA Mouse Gene IndexU026801
Consensus CDS ProjectCCDS39309.1, CCDS39310.1
International Mouse Knockout Project StatusClip2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 269713 NCBI Gene Model | MGI Sequence Detail 63049 C57BL/6J ±  kb
transcript NM_009990 RefSeq | MGI Sequence Detail 5013 C57BL/6 
polypeptide Q9Z0H8 UniProt | EBI | MGI Sequence Detail 1047 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(10) UniProt(1)
Polymorphisms PCR(1) : SNPs within 2kb(634 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000938 CAP Gly-rich domain
Protein Ontology PR:000005582 CAP-Gly domain-containing linker protein 2
Graphical View of Protein Domain Structure
References (Earliest) J:45192 De Zeeuw CI, et al., CLIP-115, a novel brain-specific cytoplasmic linker protein, mediates the localization of dendritic lamellar bodies. Neuron. 1997 Dec;19(6):1187-99
(Latest) J:194894 Couesnon A, et al., CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development. Development. 2013 Apr;140(7):1583-93
All references(44)
Other
accession IDs
MGI:1196304

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory