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Fmo5 Gene Detail
Summary
  • Symbol
    Fmo5
  • Name
    flavin containing monooxygenase 5
  • Synonyms
    5033418D19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1310004
    NCBI Gene: 14263
  • Gene Overview
    MyGene.info: FMO5
Location & Maps
more
  • Sequence Map
    Chr3:97628804-97655282 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26479 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 42.23 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    FMO5, flavin containing monooxygenase 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FMO5, flavin containing monooxygenase 5
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 2330
    neXtProt AC: NX_P49326

  • Chr Location
    1q21.1; chr1:147184300-147225798 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Fmo5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023708 VEGA Gene Model | MGI Sequence Detail 26479 C57BL/6J ±  kb
transcript OTTMUST00000058037 VEGA | MGI Sequence Detail 2453 Not Applicable  
polypeptide OTTMUSP00000028066 VEGA | MGI Sequence Detail 533 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    190 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
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MGI:1923220, MGI:2139645
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:28615 Falls JG, et al., Gender differences in hepatic expression of flavin-containing monooxygenase isoforms (FMO1, FMO3, and FMO5) in mice. J Biochem Toxicol. 1995 Jun;10(3):171-7
  • Latest
    J:223365 Gonzalez Malagon SG, et al., The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochem Pharmacol. 2015 Aug 1;96(3):267-77

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory