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Kcnj15
Gene Detail
Symbol

Name
ID
Kcnj15
potassium inwardly-rectifying channel, subfamily J, member 15
MGI:1310000
Synonyms
4930414N08Rik, IRKK, Kir4.2
Feature Type
protein coding gene
Genetic Map
Chromosome 16
55.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr16:95257558-95300211 bp, + strand
From VEGA annotation of GRCm38

  42654 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1690  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: G protein-activated inward rectifier potassium channel
Gene Tree: Kcnj15

Human
homologs
Human Homolog KCNJ15, potassium inwardly-rectifying channel, subfamily J, member 15
NCBI Gene ID 3772
neXtProt AC  NX_Q99712
Human Synonyms  IRKK, KIR1.3, KIR4.2
Human Chr (Location)  21q22.2; chr21:38229915-38303121 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous knockout mice exhibited impaired balance/coordination in a high-throughput screen.
 
Interactions
Kcnj15 interacts with 323 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (285)    Tissues (190)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 264
RT-PCR 21
cDNA source data(26)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) Genomic(2) cDNA(28) Primer pair(3)
Microarray probesets(8)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019964 VEGA Gene Model | MGI Sequence Detail 42654 C57BL/6J ±  kb
transcript OTTMUST00000047567 VEGA | MGI Sequence Detail 5705 Not Applicable 
polypeptide OTTMUSP00000021534 VEGA | MGI Sequence Detail 402 Not Applicable 

For the selected sequences
All sequences(220) RefSeq(87) UniProt(19)
Polymorphisms
SNPs within 2kb(190 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR016449 Potassium channel, inwardly rectifying, Kir
InterPro IPR003270 Potassium channel, inwardly rectifying, Kir1.3
InterPro IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
Protein Ontology PR:000001983 ATP-sensitive inward rectifier potassium channel 15
References
(Earliest) J:43272 Gosset P, et al., A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1). Genomics. 1997 Sep 1;44(2):237-41
(Latest) J:178022 He W, et al., Acid secretion-associated translocation of KCNJ15 in gastric parietal cells. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G591-600
All references(46)
Other
accession IDs
MGI:1921109, MGI:2146383, MGI:2146401

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory