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Krt34 Gene Detail
Summary
  • Symbol
    Krt34
  • Name
    keratin 34
  • Synonyms
    4733401E01Rik, Krt1-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1309994
    NCBI Gene: 16672
  • Gene Overview
    MyGene.info: KRT34
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100037347-100041554 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 63.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1309994
protein coding gene Chr11:100037347-100041554 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019136
protein coding gene Chr11:102782863-102787102 (-)
A/J MGP_AJ_G0019104
protein coding gene Chr11:98443565-98447960 (-)
AKR/J MGP_AKRJ_G0019073
protein coding gene Chr11:101486483-101492118 (-)
BALB/cJ MGP_BALBcJ_G0019078
protein coding gene Chr11:98960300-98964507 (-)
C3H/HeJ MGP_C3HHeJ_G0018887
protein coding gene Chr11:101682205-101687573 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019527
protein coding gene Chr11:105948667-105953630 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017154
protein coding gene Chr11:95896727-95900931 (-)
CAST/EiJ MGP_CASTEiJ_G0018441
protein coding gene Chr11:102663008-102667230 (-)
CBA/J MGP_CBAJ_G0018856
protein coding gene Chr11:110376355-110381557 (-)
DBA/2J MGP_DBA2J_G0018969
protein coding gene Chr11:98007898-98021503 (-)
FVB/NJ MGP_FVBNJ_G0018958
protein coding gene Chr11:97517271-97522353 (-)
LP/J MGP_LPJ_G0019037
protein coding gene Chr11:103303253-103323462 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018989
protein coding gene Chr11:110008805-110014354 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019565
protein coding gene Chr11:101861697-101866895 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0017996
protein coding gene Chr11:101555309-101560564 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KRT34, keratin 34
  • Vertebrate Orthologs
    6
  • Human Ortholog
    KRT34, keratin 34
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Ha-4, HA4, hHa4, KRTHA4
  • Links
    NCBI Gene ID: 3885
    neXtProt AC: NX_O76011
    UniProt: O76011

  • Chr Location
    17q21.2; chr17:41377650-41383816 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16672 NCBI Gene Model | MGI Sequence Detail 4208 C57BL/6J ±  kb
transcript NM_027563 RefSeq | MGI Sequence Detail 1609 C57BL/6  
polypeptide Q9D646 UniProt | EBI | MGI Sequence Detail 392 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001664 Intermediate filament protein
    IPR018039 Intermediate filament protein, conserved site
    IPR039008 Intermediate filament, rod domain
    IPR002957 Keratin, type I
Molecular
Reagents
less
  • All nucleic 26
    Genomic 2
    cDNA 24

    Microarray probesets 2
Other
Accession IDs
less
MGI:1918063
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:18490 Winter H, et al., Sequence and expression of murine type I hair keratins mHa2 and mHa3. Exp Cell Res. 1994 Jun;212(2):190-200
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory