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Trip12
Gene Detail
 Symbol
Name
ID
Trip12
thyroid hormone receptor interactor 12
MGI:1309481
Synonyms 1110036I07Rik, 6720416K24Rik, Gtl6
Feature Type protein coding gene
Genetic Map
Chromosome 1
43.42 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:84721189-84840516 bp, - strand
From VEGA annotation of GRCm38

  119328 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:44226  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Trip12

Human
homologs
Human Homolog TRIP12, thyroid hormone receptor interactor 12
NCBI Gene ID 9320
neXtProt AC  NX_Q14669
Human Synonyms  TRIP-12, ULF
Human Chr (Location)  2q36.3; chr2:229763837-229922032 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(208) : Gene trapped(203) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted allele exhibit complete embryonic lethality during organogenesis associated with embryonic growth retardation and abnormal placenta development.
 
Phenotype Images(2)
Interactions
Trip12 interacts with 411 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process cellular response to DNA damage stimulus, DNA repair, ...
Component cytoplasm, nucleoplasm, ...
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (26)    Tissues (17)    Images (2)
Theiler Stages: 22, 23, 24
Assay TypeResults
RNA in situ 26
cDNA source data(30)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(30) cDNA(30)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000048005 (Evidence)
Ensembl Gene ModelENSMUSG00000026219 (Evidence)
Entrez Gene14897 (Evidence)
DFCITC1573398, TC1594017, TC1598276, TC1605580, TC1618510
DoTSDT.101706206, DT.102558312, DT.110939136, DT.536295, DT.94155056, DT.97369357, DT.97409048
NIA Mouse Gene IndexU021545
EC6.3.2.-
Consensus CDS ProjectCCDS35633.1
International Mouse Knockout Project StatusTrip12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048005 VEGA Gene Model | MGI Sequence Detail 119328 C57BL/6J ±  kb
transcript OTTMUST00000123402 VEGA | MGI Sequence Detail 9590 Not Applicable 
polypeptide OTTMUSP00000067405 VEGA | MGI Sequence Detail 2025 Not Applicable 

For the selected sequences
All sequences(128) RefSeq(44) UniProt(3)
Polymorphisms SNPs within 2kb(476 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR000569 HECT
InterPro IPR004170 WWE domain
Protein Ontology PR:000032653 E3 ubiquitin-protein ligase TRIP12
References (Earliest) J:50092 Tate P, et al., Capturing novel mouse genes encoding chromosomal and other nuclear proteins. J Cell Sci. 1998 Sep;111(Pt 17):2575-85
(Latest) J:199251 Chen D, et al., Differential Effects on ARF Stability by Normal versus Oncogenic Levels of c-Myc Expression. Mol Cell. 2013 Jul 11;51(1):46-56
All references(43)
Other
accession IDs
MGI:1921001, MGI:2142937, MGI:2444080

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory