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Baz1a Gene Detail
Summary
  • Symbol
    Baz1a
  • Name
    bromodomain adjacent to zinc finger domain 1A
  • Synonyms
    Acf1, Gtl5, Wcrf180
  • Feature Type
    protein coding gene
  • IDs
    MGI:1309478
    NCBI Gene: 217578
  • Gene Overview
    MyGene.info: BAZ1A
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:54892989-55014348 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 23.84 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    853 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1309478
protein coding gene Chr12:54892989-55014371 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019740
protein coding gene Chr12:53846917-53971154 (-)
A/J MGP_AJ_G0019702
protein coding gene Chr12:51955190-52082071 (-)
AKR/J MGP_AKRJ_G0019673
protein coding gene Chr12:53506806-53634503 (-)
BALB/cJ MGP_BALBcJ_G0019680
protein coding gene Chr12:52229990-52360193 (-)
C3H/HeJ MGP_C3HHeJ_G0019483
protein coding gene Chr12:53622619-53751858 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020128
protein coding gene Chr12:55508658-55632861 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017751
protein coding gene Chr12:50213237-50337519 (-)
CAST/EiJ MGP_CASTEiJ_G0019036
protein coding gene Chr12:48622427-48763926 (-)
CBA/J MGP_CBAJ_G0019455
protein coding gene Chr12:57418641-57552537 (-)
DBA/2J MGP_DBA2J_G0019569
protein coding gene Chr12:51800671-51922369 (-)
FVB/NJ MGP_FVBNJ_G0019558
protein coding gene Chr12:51208595-51334175 (-)
LP/J MGP_LPJ_G0019641
protein coding gene Chr12:53909548-54034398 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019594
protein coding gene Chr12:59017269-59148943 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020166
protein coding gene Chr12:52994794-53122896 (-)
PWK/PhJ MGP_PWKPhJ_G0018803
protein coding gene Chr12:46370508-46498042 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018597
protein coding gene Chr12:47581475-47716730 (-)
WSB/EiJ MGP_WSBEiJ_G0019087
protein coding gene Chr12:53469990-53596405 (-)



Homology
more
  • Human Ortholog
    BAZ1A, bromodomain adjacent to zinc finger domain 1A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BAZ1A, bromodomain adjacent to zinc finger domain 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACF1, hACF1, WALp1, WCRF180
  • Links
    NCBI Gene ID: 11177
    neXtProt AC: NX_Q9NRL2
    UniProt: Q9NRL2

  • Chr Location
    14q13.1-q13.2; chr14:34752731-34875647 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    3 images
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable and able to repair meiotic double-strand breaks but exhibit teratospermia, oligospermia, asthenospermia, and male infertility due to impaired spermiogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035021 Ensembl Gene Model | MGI Sequence Detail 121360 C57BL/6J ±  kb
    transcript ENSMUST00000038926 Ensembl | MGI Sequence Detail 6188 Not Applicable  
    polypeptide ENSMUSP00000039757 Ensembl | MGI Sequence Detail 1555 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 216
      cDNA 215
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:3039627
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 14
    • Earliest
      J:50092 Tate P, et al., Capturing novel mouse genes encoding chromosomal and other nuclear proteins. J Cell Sci. 1998 Sep;111(Pt 17):2575-85
    • Latest
      J:244721 Sun H, et al., Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine. Neuroscience. 2017 Jun 14;353:1-6

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory