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Gtpbp6 Gene Detail
Summary
  • Symbol
    Gtpbp6
  • Name
    GTP binding protein 6 (putative)
  • Synonyms
    Pgbpll, pgpl
  • Feature Type
    protein coding gene
  • IDs
    MGI:1306825
    NCBI Gene: 107999
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:110251841-110256063 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 53.30 cM, cytoband E
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1306825
protein coding gene Chr5:110251841-110256204 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029877
protein coding gene Chr5:112525060-112529254 (-)
A/J MGP_AJ_G0029843
protein coding gene Chr5:108181490-108185682 (-)
AKR/J MGP_AKRJ_G0029781
protein coding gene Chr5:111625608-111629830 (-)
BALB/cJ MGP_BALBcJ_G0029854
protein coding gene Chr5:109551785-109555977 (-)
C3H/HeJ MGP_C3HHeJ_G0029574
protein coding gene Chr5:112050236-112054420 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030307
protein coding gene Chr5:116984578-116988800 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027536
protein coding gene Chr5:103009113-103013191 (-)
CAST/EiJ MGP_CASTEiJ_G0028982
protein coding gene Chr5:110917413-110921561 (-)
CBA/J MGP_CBAJ_G0029541
protein coding gene Chr5:121382375-121386559 (-)
DBA/2J MGP_DBA2J_G0029691
protein coding gene Chr5:108244705-108248899 (-)
FVB/NJ MGP_FVBNJ_G0029648
protein coding gene Chr5:106924445-106928803 (-)
LP/J MGP_LPJ_G0029779
protein coding gene Chr5:113097280-113101473 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029679
protein coding gene Chr5:126040298-126044491 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030348
protein coding gene Chr5:111055380-111059574 (-)
PWK/PhJ MGP_PWKPhJ_G0028696
protein coding gene Chr5:106840400-106844612 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028534
protein coding gene Chr5:108525721-108529928 (-)
WSB/EiJ MGP_WSBEiJ_G0029058
protein coding gene Chr5:111506980-111511169 (-)



Homology
more
  • Human Ortholog
    GTPBP6, GTP binding protein 6 (putative)
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTPBP6, GTP binding protein 6 (putative)
  • Synonyms
    PGPL
  • Links
    NCBI Gene ID: 8225
    neXtProt AC: NX_O43824
    UniProt: O43824

  • Chr Location
    XY;Y

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033434 Ensembl Gene Model | MGI Sequence Detail 4223 C57BL/6J ±  kb
transcript ENSMUST00000077220 Ensembl | MGI Sequence Detail 1617 Not Applicable  
polypeptide ENSMUSP00000076458 Ensembl | MGI Sequence Detail 514 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 41

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141116
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory