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Gtpbp6 Gene Detail
Summary
  • Symbol
    Gtpbp6
  • Name
    GTP binding protein 6 (putative)
  • Synonyms
    Pgbpll, pgpl
  • Feature Type
    protein coding gene
  • IDs
    MGI:1306825
    NCBI Gene: 107999
  • Gene Overview
    MyGene.info: GTPBP6
Location & Maps
more
  • Sequence Map
    Chr5:110103975-110108197 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4223 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 53.30 cM, cytoband E
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GTPBP6, GTP binding protein 6 (putative)
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GTPBP6, GTP binding protein 6 (putative)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PGPL
  • Links
    NCBI Gene ID: 8225
    neXtProt AC: NX_O43824

  • Chr Location
    XYp22.33 and Yp11.31

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Gtpbp6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026198 VEGA Gene Model | MGI Sequence Detail 4223 C57BL/6J ±  kb
transcript OTTMUST00000064742 VEGA | MGI Sequence Detail 1617 Not Applicable  
polypeptide OTTMUSP00000032194 VEGA | MGI Sequence Detail 514 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    58 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR016496 GTPase HflX
    IPR025121 GTPase HflX, N-terminal
    IPR006073 GTP binding domain
    IPR032305 GTP-binding protein, middle domain
    IPR030394 HflX-type guanine nucleotide-binding (G) domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 40
    cDNA 40

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141116
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:46367 Gianfrancesco F, et al., A novel pseudoautosomal gene encoding a putative GTP-binding protein resides in the vicinity of the Xp/Yp telomere. Hum Mol Genet. 1998 Mar;7(3):407-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory