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Gtpbp6 Gene Detail
Summary
  • Symbol
    Gtpbp6
  • Name
    GTP binding protein 6 (putative)
  • Synonyms
    Pgbpll, pgpl
  • Feature Type
    protein coding gene
  • IDs
    MGI:1306825
    NCBI Gene: 107999
  • Gene Overview
    MyGene.info: GTPBP6
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:110103976-110108197 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 53.30 cM, cytoband E
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1306825
protein coding gene Chr5:110103975-110108197 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029877
protein coding gene Chr5:112525060-112529254 (-)
A/J MGP_AJ_G0029843
protein coding gene Chr5:108181490-108185682 (-)
AKR/J MGP_AKRJ_G0029781
protein coding gene Chr5:111625608-111629830 (-)
BALB/cJ MGP_BALBcJ_G0029854
protein coding gene Chr5:109551785-109555977 (-)
C3H/HeJ MGP_C3HHeJ_G0029574
protein coding gene Chr5:112050236-112054420 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030307
protein coding gene Chr5:116984578-116988800 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027536
protein coding gene Chr5:103009113-103013191 (-)
CAST/EiJ MGP_CASTEiJ_G0028982
protein coding gene Chr5:110917413-110921561 (-)
CBA/J MGP_CBAJ_G0029541
protein coding gene Chr5:121382375-121386559 (-)
DBA/2J MGP_DBA2J_G0029691
protein coding gene Chr5:108244705-108248899 (-)
FVB/NJ MGP_FVBNJ_G0029648
protein coding gene Chr5:106924445-106928803 (-)
LP/J MGP_LPJ_G0029779
protein coding gene Chr5:113097280-113101473 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029679
protein coding gene Chr5:126040298-126044491 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030348
protein coding gene Chr5:111055380-111059574 (-)
PWK/PhJ MGP_PWKPhJ_G0028696
protein coding gene Chr5:106840400-106844612 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028534
protein coding gene Chr5:108525721-108529928 (-)
WSB/EiJ MGP_WSBEiJ_G0029058
protein coding gene Chr5:111506980-111511169 (-)



Homology
more
  • Human Ortholog
    GTPBP6, GTP binding protein 6 (putative)
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GTPBP6, GTP binding protein 6 (putative)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PGPL
  • Links
    NCBI Gene ID: 8225
    neXtProt AC: NX_O43824
    UniProt: O43824

  • Chr Location
    XYp22.33 and Yp11.31

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 107999 NCBI Gene Model | MGI Sequence Detail 4222 C57BL/6J ±  kb
transcript NM_145147 RefSeq | MGI Sequence Detail 1615 C57BL/6  
polypeptide Q3U6U5 UniProt | EBI | MGI Sequence Detail 514 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR016496 GTPase HflX
    IPR025121 GTPase HflX, N-terminal
    IPR006073 GTP binding domain
    IPR032305 GTP-binding protein, middle domain
    IPR030394 HflX-type guanine nucleotide-binding (G) domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 41
    cDNA 41

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141116
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory