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Vwa7 Gene Detail
Summary
  • Symbol
    Vwa7
  • Name
    von Willebrand factor A domain containing 7
  • Synonyms
    D17H6S56E-3, G7c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1306798
    NCBI Gene: 27762
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35016579-35026741 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.55 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1306798
protein coding gene Chr17:35016358-35026741 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023606
protein coding gene Chr17:35149060-35159475 (+)
A/J MGP_AJ_G0023566
protein coding gene Chr17:33990823-34000991 (+)
AKR/J MGP_AKRJ_G0023534
protein coding gene Chr17:34460138-34470296 (+)
BALB/cJ MGP_BALBcJ_G0023572
protein coding gene Chr17:34120871-34131022 (+)
C3H/HeJ MGP_C3HHeJ_G0023333
protein coding gene Chr17:34855544-34865711 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024011
protein coding gene Chr17:36490325-36502090 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021492
protein coding gene Chr17:31757161-31767340 (+)
CAST/EiJ MGP_CASTEiJ_G0022830
protein coding gene Chr17:34858919-34869095 (+)
CBA/J MGP_CBAJ_G0023311
protein coding gene Chr17:38001019-38011314 (+)
DBA/2J MGP_DBA2J_G0023439
protein coding gene Chr17:33308982-33319497 (+)
FVB/NJ MGP_FVBNJ_G0023406
protein coding gene Chr17:33145266-33155671 (+)
LP/J MGP_LPJ_G0023516
protein coding gene Chr17:35476911-35488265 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023428
protein coding gene Chr17:36931322-36941473 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024056
protein coding gene Chr17:34684354-34694514 (+)
PWK/PhJ MGP_PWKPhJ_G0022577
protein coding gene Chr17:32140519-32150844 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022397
protein coding gene Chr17:32694116-32704300 (+)
WSB/EiJ MGP_WSBEiJ_G0022893
protein coding gene Chr17:34797314-34807465 (+)



Homology
more
  • Human Ortholog
    VWA7, von Willebrand factor A domain containing 7
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VWA7, von Willebrand factor A domain containing 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf27, G7c, NG37
  • Links
    NCBI Gene ID: 80737
    neXtProt AC: NX_Q9Y334
    UniProt: Q9Y334

  • Chr Location
    6p21.33; chr6:31764135-31777331 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11895
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: VWA7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000007030 Ensembl Gene Model | MGI Sequence Detail 10163 C57BL/6J ±  kb
transcript ENSMUST00000007245 Ensembl | MGI Sequence Detail 4313 Not Applicable  
polypeptide ENSMUSP00000007245 Ensembl | MGI Sequence Detail 891 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000030430 von Willebrand factor A domain-containing protein 7
  • InterPro Domains
    IPR036465 von Willebrand factor A-like domain superfamily
Molecular
Reagents
less
  • All nucleic 5
    Genomic 3
    cDNA 2

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:44921 Snoek M, et al., Molecular analysis of the major MHC recombinational hot spot located within the G7c gene of the murine class III region that is involved in disease susceptibility. J Immunol. 1998 Jan 1;160(1):266-72
  • Latest
    J:73829 van Kooij M, et al., Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region. Immunogenetics. 2001 Oct;53(8):656-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory