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Map1b
Gene Detail
 Symbol
Name
ID
Map1b
microtubule-associated protein 1B
MGI:1306778
Synonyms LC1, MAP5, Mtap1b, Mtap5, Mtap-5
Feature Type protein coding gene
Genetic Map
Chromosome 13
52.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(18)
Sequence Map
Chr13:99421464-99516602 bp, - strand
From NCBI annotation of GRCm38

  95139 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38111  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Map1b

Human
homologs
Human Homolog MAP1B, microtubule-associated protein 1B
NCBI Gene ID 4131
neXtProt AC  NX_P46821
Human Synonyms  FUTSCH, MAP5, PPP1R102
Human Chr (Location)  5q13; chr5:72107291-72209570 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(9) Targeted(3)
Incidental mutations (data from APF )
 
Mice homozygous for one knock-out allele die prior to E8.5. While mice homozygous for other knock-out alleles exhibit behavioral, visual system, and nervous system defects.
 
Interactions
Map1b interacts with 503 markers (Mir1b, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (46 annotations)
Process axon extension, axonogenesis, ...
Component axon, cell, ...
Function actin binding, cytoskeletal regulatory protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (20 records)
Data Summary: Results (241)    Tissues (88)    Images (40)
Theiler Stages: 15, 17, 19, 21, 22, 23, 26, 27, 28
Assay TypeResults
Immunohistochemistry 8
RNA in situ 194
Northern blot 3
Western blot 24
RT-PCR 12
cDNA source data(31)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) Genomic(4) cDNA(35) Primer pair(8) Other(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000052727 (Evidence)
Entrez Gene17755 (Evidence)
DoTSDT.101145779, DT.101405362, DT.110969967, DT.87045615, DT.94239073, DT.97369708, DT.97382016, DT.97382023, DT.97389737
NIA Mouse Gene IndexU035097, U153767
Consensus CDS ProjectCCDS26723.1
International Mouse Knockout Project StatusMap1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 17755 NCBI Gene Model | MGI Sequence Detail 95139 C57BL/6J ±  kb
transcript NM_008634 RefSeq | MGI Sequence Detail 11852 C57BL/6 
polypeptide P14873 UniProt | EBI | MGI Sequence Detail 2464 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(4) UniProt(9)
Polymorphisms All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs within 2kb(508 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001279 Beta-lactamase-like
InterPro IPR026074 Microtubule associated protein 1
InterPro IPR027321 Microtubule-associated protein 1B
InterPro IPR000102 Neuraxin/MAP1B repeat
Protein Ontology PR:000010117 microtubule-associated protein 1B
Graphical View of Protein Domain Structure
References (Earliest) J:34302 Noble M, et al., The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau. J Cell Biol. 1989 Dec;109(6 Pt 2):3367-76
(Latest) J:209602 Li CL, et al., SRF phosphorylation by glycogen synthase kinase-3 promotes axon growth in hippocampal neurons. J Neurosci. 2014 Mar 12;34(11):4027-42
All references(98)
Other
accession IDs
MGD-MRK-12583, MGD-MRK-12589, MGI:2145294, MGI:97179

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory