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Map1a
Gene Detail
Symbol

Name
ID
Map1a
microtubule-associated protein 1 A
MGI:1306776
Synonyms
6330416M19Rik, Mtap1, Mtap-1, Mtap1a
Feature Type
protein coding gene
Genetic Map
Chromosome 2
60.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(16)
Sequence Map
Chr2:121289600-121310832 bp, + strand
From VEGA annotation of GRCm38

  21233 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1778  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: MAP1A
Gene Tree: Map1a

Human
homologs
MAP1A, microtubule-associated protein 1A
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4130
neXtProt AC: NX_P78559

Human Synonyms: MAP1L, MTAP1A

Human Chr (Location): 15q15.3; chr15:43517608-43531620 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(17) QTL(2) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Map1a interacts with 400 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process activation of mitophagy in response to mitochondrial depolarization, microtubule cytoskeleton organization, ...
Component cytoplasm, cytoskeleton, ...
Function actin binding, collagen binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (3)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
Western blot 3
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase map1a    NEW 
Molecular
reagents
All nucleic(11) cDNA(10) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000015225 (Evidence)
Ensembl Gene Model ENSMUSG00000027254 (Evidence)
Entrez Gene 17754 (Evidence)
NIA Mouse Gene Index U042352
Consensus CDS Project CCDS38215.1, CCDS50685.1
International Mouse Phenotyping Consortium Status Map1a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015225 VEGA Gene Model | MGI Sequence Detail 21233 C57BL/6J ±  kb
transcript OTTMUST00000036069 VEGA | MGI Sequence Detail 11825 Not Applicable 
polypeptide OTTMUSP00000016203 VEGA | MGI Sequence Detail 3014 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(6) UniProt(2)
Polymorphisms
RFLP(3) : SNPs within 2kb(102 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001279 Beta-lactamase-like
InterPro IPR026074 Microtubule associated protein 1
InterPro IPR015656 Microtubule associated protein 1A
Protein Ontology PR:000010116 microtubule-associated protein 1A
References
(Earliest) J:10560 Garner CC, et al., Molecular cloning of microtubule-associated protein 1 (MAP1A) and microtubule-associated protein 5 (MAP1B): identification of distinct genes and their differential expression in developing brain. J Neurochem. 1990 Jul;55(1):146-54
(Latest) J:218247 Cossette SM, et al., Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Biol Open. 2014;4(1):48-61
All references(57)
Other
accession IDs
MGD-MRK-12579, MGD-MRK-12584, MGI:1346024, MGI:1921253, MGI:2139097, MGI:97174

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory