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Plp2
Gene Detail
Symbol

Name
ID
Plp2
proteolipid protein 2
MGI:1298382
Synonyms
mIMA4
Feature Type
protein coding gene
Genetic Map
Chromosome X
3.45 cM, cytoband A2-A3.1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:7667941-7671390 bp, - strand
From VEGA annotation of GRCm38

  3450 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2003  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PLP2
Gene Tree: Plp2

Human
homologs
PLP2, proteolipid protein 2 (colonic epithelium-enriched)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5355
neXtProt AC: NX_Q04941

Human Synonyms: A4, A4LSB

Human Chr (Location): Xp11.23; chrX:49171837-49175120 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(12) Targeted(3)
Incidental mutations (data from CvDC )
Interactions
Plp2 interacts with 80 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Component extracellular exosome, plasma membrane
Function chemokine binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (76)    Tissues (33)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 76
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase plp2 ; ZFIN plp2    NEW 
Molecular
reagents
All nucleic(20) Genomic(5) cDNA(15)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000017753 (Evidence)
Ensembl Gene Model ENSMUSG00000031146 (Evidence)
Entrez Gene 18824 (Evidence)
DFCI TC1574266, TC1721587, TC1730194
NIA Mouse Gene Index U039229, U080706, U065891
Consensus CDS Project CCDS40842.1
International Mouse Phenotyping Consortium Status Plp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017753 VEGA Gene Model | MGI Sequence Detail 3450 C57BL/6J ±  kb
transcript OTTMUST00000042983 VEGA | MGI Sequence Detail 1157 Not Applicable 
polypeptide OTTMUSP00000019327 VEGA | MGI Sequence Detail 152 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2)
Polymorphisms
SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000012880 proteolipid protein 2
References
(Earliest) J:49742 Kuroiwa A, et al., Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes. Cytogenet Cell Genet. 1998;81(3-4):208-12
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory