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Matr3 Gene Detail
Summary
  • Symbol
    Matr3
  • Name
    matrin 3
  • Synonyms
    1110061A14Rik, 2810017I02Rik, D030046F20Rik, mKIAA0723
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298379
    NCBI Gene: 17184
Location & Maps
more
  • Sequence Map
    Chr18:35562146-35593835 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31690 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MATR3, matrin 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MATR3, matrin 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ALS21, MPD2, VCPDM
  • Links
    NCBI Gene ID: 9782
    neXtProt AC: NX_P43243

  • Chr Location
    5q31.2; chr5:139273752-139331677 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human MATR3 associations

Human Disease Mouse Models
       Amyotrophic Lateral Sclerosis 21; ALS21   OMIM: 606070
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045440 VEGA Gene Model | MGI Sequence Detail 31690 C57BL/6J ±  kb
transcript OTTMUST00000119211 VEGA | MGI Sequence Detail 6262 Not Applicable  
polypeptide OTTMUSP00000066390 VEGA | MGI Sequence Detail 846 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    73 from dbSNP Build 137
  • RFLP
Protein
Information
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Molecular
Reagents
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  • All nucleic 32
    Genomic 1
    cDNA 27
    Primer pair 3
    Other 1

    Microarray probesets 11
Other
Accession IDs
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MGI:1916077, MGI:1917217, MGI:2147265, MGI:2147377, MGI:3026954
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:49740 Matsushima Y, et al., Cloning and genomic mapping of the mouse matrin 3 gene and its pseudogenes. Cytogenet Cell Genet. 1998;81(3-4):194-8
  • Latest
    J:220876 Quintero-Rivera F, et al., MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus. Hum Mol Genet. 2015 Apr 15;24(8):2375-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory