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Naip1
Gene Detail
Symbol

Name
ID
Naip1
NLR family, apoptosis inhibitory protein 1
MGI:1298223
Synonyms
Birc1a, D13Lsd1, Naip
Feature Type
protein coding gene
Genetic Map
Chromosome 13
53.18 cM, cytoband D1-D3
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
Chr13:100407770-100446406 bp, - strand
From Ensembl annotation of GRCm38

  38637 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:113589  Vertebrate Homology Class
3 mouse; 2 rat

Protein SuperFamily: neuronal apoptosis inhibitory protein
Gene Tree: Naip1

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display a normal phenotype.
 
Interactions
Naip1 interacts with 185 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process apoptotic process, cellular response to estrogen stimulus, ...
Component basolateral plasma membrane, cytoplasm, ...
Function ATP binding, cysteine-type endopeptidase inhibitor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (122)    Tissues (68)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
In situ reporter (knock in) 48
RT-PCR 50
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(36) Genomic(20) cDNA(9) Primer pair(6) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000021640 (Evidence)
Entrez Gene17940 (Evidence)
UniGene6898
DoTSDT.485607, DT.91335568
NIA Mouse Gene IndexU035107
Consensus CDS ProjectCCDS26729.1
International Mouse Knockout Project StatusNaip1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021640 Ensembl Gene Model | MGI Sequence Detail 38637 C57BL/6J ±  kb
transcript ENSMUST00000022142 Ensembl | MGI Sequence Detail 5353 Not Applicable 
polypeptide ENSMUSP00000022142 Ensembl | MGI Sequence Detail 1403 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(6) UniProt(2)
Polymorphisms
PCR(3) : SNPs within 2kb(383 from dbSNP Build 137)    SNPs within 2kb including multiple locations(435)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR001370 Baculoviral inhibition of apoptosis protein repeat
InterPro IPR007111 NACHT nucleoside triphosphatase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000011552 baculoviral IAP repeat-containing protein 1a
References
(Earliest) J:37707 Scharf JM, et al., The mouse region syntenic for human spinal muscular atrophy lies within the Lgn1 critical interval and contains multiple copies of Naip exon 5. Genomics. 1996 Dec 15;38(3):405-17
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(47)
Other
accession IDs
MGD-MRK-38374, MGD-MRK-39477, MGI:109329, MGI:109478, MGI:2145401

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory