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Naip6
Gene Detail
 Symbol
Name
ID
Naip6
NLR family, apoptosis inhibitory protein 6
MGI:1298222
Synonyms Birc1f, Naip-rs4, Naip-rs4A
Feature Type protein coding gene
Genetic Map
Chromosome 13
53.09 cM, cytoband D1-D3
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr13:100281121-100317674 bp, - strand
From VEGA annotation of GRCm38

  36554 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:113589  Vertebrate Homology Class
3 mouse; 2 rat

Protein SuperFamily: neuronal apoptosis inhibitory protein
Gene Tree: Naip6

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Naip6 interacts with 320 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process apoptotic process, cellular response to estrogen stimulus, ...
Component cytoplasm, IPAF inflammasome complex, ...
Function ATP binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (23)    Tissues (21)    Images (2)
Theiler Stages: 17, 22, 23, 28
Assay TypeResults
RNA in situ 13
RT-PCR 10
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) Genomic(9) cDNA(3) Primer pair(3) Other(1)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000028714 (Evidence)
Ensembl Gene ModelENSMUSG00000078942 (Evidence)
Entrez Gene17952 (Evidence)
Consensus CDS ProjectCCDS26728.1
International Mouse Knockout Project StatusNaip6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028714 VEGA Gene Model | MGI Sequence Detail 36554 C57BL/6J ±  kb
transcript OTTMUST00000071113 VEGA | MGI Sequence Detail 6827 Not Applicable 
polypeptide OTTMUSP00000036369 VEGA | MGI Sequence Detail 1403 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(12) UniProt(3)
Polymorphisms PCR(2) : SNPs within 2kb(295 from dbSNP Build 137)    SNPs within 2kb including multiple locations(411)
Protein-related
information
ResourceIDDescription
InterPro IPR001370 Baculoviral inhibition of apoptosis protein repeat
InterPro IPR007111 NACHT nucleoside triphosphatase
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000011555 baculoviral IAP repeat-containing protein 1f
References (Earliest) J:37707 Scharf JM, et al., The mouse region syntenic for human spinal muscular atrophy lies within the Lgn1 critical interval and contains multiple copies of Naip exon 5. Genomics. 1996 Dec 15;38(3):405-17
(Latest) J:176197 Kofoed EM, et al., Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature. 2011 Sep 29;477(7366):592-5
All references(28)
Other
accession IDs
MGD-MRK-38481, MGI:109436

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory