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Cst7 Gene Detail
Summary
  • Symbol
    Cst7
  • Name
    cystatin F (leukocystatin)
  • Synonyms
    CMAP, cystatin-like metastasis-associated protein, Leukocystatin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298217
    NCBI Gene: 13011
  • Gene Overview
    MyGene.info: CST7
Location & Maps
more
  • Sequence Map
    Chr2:150570415-150578944 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8530 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 74.67 cM, cytoband G1-G3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CST7, cystatin F
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CST7, cystatin F
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CMAP
  • Links
    NCBI Gene ID: 8530
    neXtProt AC: NX_O76096

  • Chr Location
    20p11.21; chr20:24949230-24959928 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 37832
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CST7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Cst7
  • Incidental Mutations
Homozygous mutation of this gene results in no abnormal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015741 VEGA Gene Model | MGI Sequence Detail 8530 C57BL/6J ±  kb
transcript OTTMUST00000037389 VEGA | MGI Sequence Detail 986 Not Applicable  
polypeptide OTTMUSP00000016750 VEGA | MGI Sequence Detail 144 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    97 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    Genomic 2
    cDNA 18
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:48319 Halfon S, et al., Leukocystatin, a new Class II cystatin expressed selectively by hematopoietic cells. J Biol Chem. 1998 Jun 26;273(26):16400-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory