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Zkscan6 Gene Detail
Summary
  • Symbol
    Zkscan6
  • Name
    zinc finger with KRAB and SCAN domains 6
  • Synonyms
    1700128E15Rik, D11Ertd714e, KOX11, Zfp535
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289293
    NCBI Gene: 52712
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:65698001-65720065 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 40.53 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289293
protein coding gene Chr11:65697980-65720065 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018478
protein coding gene Chr11:66026103-66048212 (+)
A/J MGP_AJ_G0018447
protein coding gene Chr11:63573867-63595930 (+)
AKR/J MGP_AKRJ_G0018416
protein coding gene Chr11:65467825-65489883 (+)
BALB/cJ MGP_BALBcJ_G0018418
protein coding gene Chr11:63828053-63850087 (+)
C3H/HeJ MGP_C3HHeJ_G0018231
protein coding gene Chr11:65476045-65498099 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018870
protein coding gene Chr11:68030564-68052617 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016514
protein coding gene Chr11:60578308-60601358 (+)
CAST/EiJ MGP_CASTEiJ_G0017787
protein coding gene Chr11:65702339-65724366 (+)
CBA/J MGP_CBAJ_G0018205
protein coding gene Chr11:71014066-71036103 (+)
DBA/2J MGP_DBA2J_G0018314
protein coding gene Chr11:63109750-63131797 (+)
FVB/NJ MGP_FVBNJ_G0018304
protein coding gene Chr11:62772328-62794367 (+)
LP/J MGP_LPJ_G0018386
protein coding gene Chr11:66549153-66571207 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018328
protein coding gene Chr11:71900160-71922208 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018911
protein coding gene Chr11:65706390-65728433 (+)
PWK/PhJ MGP_PWKPhJ_G0017561
protein coding gene Chr11:63757900-63784956 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017351
protein coding gene Chr11:65545031-65567173 (+)
WSB/EiJ MGP_WSBEiJ_G0017840
protein coding gene Chr11:65299603-65321645 (+)



Homology
more
  • Human Ortholog
    ZNF18, zinc finger protein 18
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF18, zinc finger protein 18
  • Synonyms
    HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38
  • Links
    NCBI Gene ID: 7566
    neXtProt AC: NX_P17022
    UniProt: P17022

  • Chr Location
    17p12; chr17:11977439-12021527 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018347 Ensembl Gene Model | MGI Sequence Detail 22065 C57BL/6J ±  kb
transcript ENSMUST00000071465 Ensembl | MGI Sequence Detail 2270 Not Applicable  
polypeptide ENSMUSP00000071406 Ensembl | MGI Sequence Detail 556 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 27
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:1914613
References
more
  • Summaries
    All 39
    Developmental Gene Expression 6
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory