Ppp1r10
Gene Detail

Symbol Name ID

Ppp1r10 protein phosphatase 1, regulatory subunit 10 MGI:1289273

Synonyms

2610025H06Rik, D17Ertd808e, PNUTS

Feature Type

protein coding gene

Genetic Map

Chromosome 17

18.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:35916434-35932272 bp, + strand From VEGA annotation of GRCm38   15839 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2033  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Ppp1r10

Human homologs

Human Homolog		PPP1R10, protein phosphatase 1, regulatory subunit 10
NCBI Gene ID		5514
neXtProt AC		NX_Q96QC0
Human Synonyms		CAT53, FB19, p99, PNUTS, PP1R10, R111
Human Chr (Location)		6p21.3; chr6:30568177-30585084 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(116) : Targeted(2) Gene trapped(113) Transgenic(1)
 

Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.

 

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	transcription, DNA-dependent
Component	chromatin, nuclear chromatin, ...
Function	DNA binding, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (28)    Tissues (20)   
Theiler Stages: 2, 3, 4, 5, 24, 26, 28

Assay Type	Results
RNA in situ	13
RT-PCR	15

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(18) cDNA(16) Primer pair(2)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000021047 (Evidence)
Ensembl Gene Model	ENSMUSG00000039220 (Evidence)
Entrez Gene	52040 (Evidence)
NIA Mouse Gene Index	U043598
Consensus CDS Project	CCDS50098.1
International Mouse Knockout Project Status	Ppp1r10

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021047	VEGA Gene Model | MGI Sequence Detail	15839	C57BL/6J
transcript	OTTMUST00000049786	VEGA | MGI Sequence Detail	4244	Not Applicable
polypeptide	OTTMUSP00000023122	VEGA | MGI Sequence Detail	888	Not Applicable

All sequences(46) RefSeq(3) UniProt(4)

Polymorphisms

SNPs(51 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003617	Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
InterPro	IPR017923	Transcription factor IIS, N-terminal
InterPro	IPR000571	Zinc finger, CCCH-type
Protein Ontology	PR:000013105	serine/threonine-protein phosphatase 1 regulatory subunit 10

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:168381 Lee JH, et al., Identification and characterization of a novel human PP1 phosphatase complex. J Biol Chem. 2010 Aug 6;285(32):24466-76
All references(39)

Other accession IDs

MGI:1913700