About   Help   FAQ
Echdc2 Gene Detail
Summary
  • Symbol
    Echdc2
  • Name
    enoyl Coenzyme A hydratase domain containing 2
  • Synonyms
    1300017C12Rik, 2610009M20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289238
    NCBI Gene: 52430
Location & Maps
more
  • Sequence Map
    Chr4:108165437-108179308 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13872 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 50.30 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ECHDC2, enoyl-CoA hydratase domain containing 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ECHDC2, enoyl-CoA hydratase domain containing 2
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 55268
    neXtProt AC: NX_Q86YB7

  • Chr Location
    1p32.3; chr1:52895910-52927212 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Echdc2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009483 VEGA Gene Model | MGI Sequence Detail 13872 C57BL/6J ±  kb
transcript OTTMUST00000021627 VEGA | MGI Sequence Detail 1307 Not Applicable  
polypeptide OTTMUSP00000009876 VEGA | MGI Sequence Detail 296 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    232 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000029436 enoyl-CoA hydratase domain-containing protein 2, mitochondrial
  • InterPro Domains
    IPR029045 ClpP/crotonase-like domain
    IPR014748 Crontonase, C-terminal
    IPR001753 Crotonase superfamily
    IPR018376 Enoyl-CoA hydratase/isomerase, conserved site
Molecular
Reagents
less
  • All nucleic 96
    cDNA 94
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915695, MGI:1917149
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory