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Zwint Gene Detail
Summary
  • Symbol
    Zwint
  • Name
    ZW10 interactor
  • Synonyms
    2010007E07Rik, 2600001N01Rik, D10Ertd749e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289227
    NCBI Gene: 52696
  • Gene Overview
    MyGene.info: ZWINT
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:72654846-72674964 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 37.15 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    161 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289227
protein coding gene Chr10:72654845-72674964 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017346
protein coding gene Chr10:72710372-72730394 (+)
A/J MGP_AJ_G0017323
protein coding gene Chr10:70258084-70278189 (+)
AKR/J MGP_AKRJ_G0017284
protein coding gene Chr10:72119327-72139419 (+)
BALB/cJ MGP_BALBcJ_G0017283
protein coding gene Chr10:70385364-70405401 (+)
C3H/HeJ MGP_C3HHeJ_G0017107
protein coding gene Chr10:72127507-72147655 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017741
protein coding gene Chr10:75254313-75280634 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015431
protein coding gene Chr10:66609885-66629926 (+)
CAST/EiJ MGP_CASTEiJ_G0016677
protein coding gene Chr10:72284523-72305789 (+)
CBA/J MGP_CBAJ_G0017079
protein coding gene Chr10:78183018-78206643 (+)
DBA/2J MGP_DBA2J_G0017184
protein coding gene Chr10:69545362-69565349 (+)
FVB/NJ MGP_FVBNJ_G0017177
protein coding gene Chr10:68690450-68710547 (+)
LP/J MGP_LPJ_G0017257
protein coding gene Chr10:73170297-73190362 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017205
protein coding gene Chr10:80256592-80277700 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017780
protein coding gene Chr10:72107084-72127215 (+)
PWK/PhJ MGP_PWKPhJ_G0016461
protein coding gene Chr10:69363852-69384808 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016244
protein coding gene Chr10:71384534-71404713 (+)
WSB/EiJ MGP_WSBEiJ_G0016741
protein coding gene Chr10:72101434-72121571 (+)



Homology
more
  • Human Ortholog
    ZWINT, ZW10 interacting kinetochore protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ZWINT, ZW10 interacting kinetochore protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HZwint-1, KNTC2AP, SIP30, ZWINT1
  • Links
    NCBI Gene ID: 11130
    neXtProt AC: NX_O95229
    UniProt: O95229

  • Chr Location
    10q21.1; chr10:56357257-56361302 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Zwint
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 52696 NCBI Gene Model | MGI Sequence Detail 20119 C57BL/6J ±  kb
transcript NM_025635 RefSeq | MGI Sequence Detail 2729 C57BL/6  
polypeptide Q9CQU5 UniProt | EBI | MGI Sequence Detail 252 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 299
    cDNA 297
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGI:1913814, MGI:1917100
References
more
  • Summaries
    All 42
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:246912 Ye A, et al., PEG3 control on the mammalian MSL complex. PLoS One. 2017;12(6):e0178363

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory