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Tmem41b Gene Detail
Summary
  • Symbol
    Tmem41b
  • Name
    transmembrane protein 41B
  • Synonyms
    1500015G02Rik, 1500031M19Rik, D7Ertd70e, D7Ertd743e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289225
    NCBI Gene: 233724
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:109972187-109986230 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 57.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289225
protein coding gene Chr7:109972187-109986929 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032851
protein coding gene Chr7:113430822-113446487 (-)
A/J MGP_AJ_G0032835
protein coding gene Chr7:110621732-110634165 (-)
AKR/J MGP_AKRJ_G0032766
protein coding gene Chr7:113403171-113418425 (-)
BALB/cJ MGP_BALBcJ_G0032839
protein coding gene Chr7:110318329-110332446 (-)
C3H/HeJ MGP_C3HHeJ_G0032549
protein coding gene Chr7:113430426-113449631 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033345
protein coding gene Chr7:118133815-118150839 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030318
protein coding gene Chr7:112191925-112209445 (-)
CAST/EiJ MGP_CASTEiJ_G0031877
protein coding gene Chr7:104967988-104984136 (-)
CBA/J MGP_CBAJ_G0032522
protein coding gene Chr7:121992796-122012809 (-)
DBA/2J MGP_DBA2J_G0032674
protein coding gene Chr7:108727357-108743196 (-)
FVB/NJ MGP_FVBNJ_G0032627
protein coding gene Chr7:108581261-108597897 (-)
LP/J MGP_LPJ_G0032768
protein coding gene Chr7:114961316-114978072 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032659
protein coding gene Chr7:123652467-123673402 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033366
protein coding gene Chr7:112410131-112426173 (-)
PWK/PhJ MGP_PWKPhJ_G0031584
protein coding gene Chr7:101538088-101553868 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031432
protein coding gene Chr7:99113867-99130516 (-)
WSB/EiJ MGP_WSBEiJ_G0031990
protein coding gene Chr7:113259559-113274869 (-)



Homology
more
  • Human Ortholog
    TMEM41B, transmembrane protein 41B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM41B, transmembrane protein 41B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 440026
    neXtProt AC: NX_Q5BJD5
    UniProt: Q5BJD5

  • Chr Location
    11p15.4; chr11:9280654-9314768 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 233724 NCBI Gene Model | MGI Sequence Detail 14044 C57BL/6J ±  kb
transcript NM_153525 RefSeq | MGI Sequence Detail 3619 C57BL/6  
polypeptide Q8K1A5 UniProt | EBI | MGI Sequence Detail 291 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 34
    Primer pair 2

    Microarray probesets 11
Other
Accession IDs
less
MGI:1098618, MGI:1916268, MGI:1923591, MGI:2143199
References
more
  • Summaries
    All 43
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:189067 Lotti F, et al., An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function. Cell. 2012 Oct 12;151(2):440-54

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory