About   Help   FAQ
Trmt1 Gene Detail
Summary
  • Symbol
    Trmt1
  • Name
    tRNA methyltransferase 1
  • Synonyms
    6720406L13Rik, D8Ertd812e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289155
    NCBI Gene: 212528
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:84686312-84699808 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 41.02 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289155
protein coding gene Chr8:84686307-84699808 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033866
protein coding gene Chr8:85597830-85612585 (+)
A/J MGP_AJ_G0033849
protein coding gene Chr8:82227562-82242269 (+)
AKR/J MGP_AKRJ_G0033775
protein coding gene Chr8:84662379-84676142 (+)
BALB/cJ MGP_BALBcJ_G0033842
protein coding gene Chr8:82350678-82364921 (+)
C3H/HeJ MGP_C3HHeJ_G0033552
protein coding gene Chr8:85278159-85297704 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034362
protein coding gene Chr8:88885547-88904811 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031304
protein coding gene Chr8:76021312-76034908 (+)
CAST/EiJ MGP_CASTEiJ_G0032882
protein coding gene Chr8:84702451-84720797 (+)
CBA/J MGP_CBAJ_G0033528
protein coding gene Chr8:91931514-91947709 (+)
DBA/2J MGP_DBA2J_G0033681
protein coding gene Chr8:81868815-81883157 (+)
FVB/NJ MGP_FVBNJ_G0033629
protein coding gene Chr8:80806032-80820210 (+)
LP/J MGP_LPJ_G0033773
protein coding gene Chr8:85711141-85726940 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033671
protein coding gene Chr8:94476113-94492916 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034379
protein coding gene Chr8:84652517-84665941 (+)
PWK/PhJ MGP_PWKPhJ_G0032586
protein coding gene Chr8:81111842-81125607 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032422
protein coding gene Chr8:83462466-83476992 (+)
WSB/EiJ MGP_WSBEiJ_G0032995
protein coding gene Chr8:85078397-85096721 (+)



Homology
more
  • Human Ortholog
    TRMT1, tRNA methyltransferase 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TRMT1, tRNA methyltransferase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TRM1
  • Links
    NCBI Gene ID: 55621
    neXtProt AC: NX_Q9NXH9
    UniProt: Q9NXH9

  • Chr Location
    19p13.13; chr19:13104900-13117568 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5632
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TRMT1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    38 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 212528 NCBI Gene Model | MGI Sequence Detail 13497 C57BL/6J ±  kb
transcript NM_001364176 RefSeq | MGI Sequence Detail 2356 C57BL/6  
polypeptide Q3TX08 UniProt | EBI | MGI Sequence Detail 663 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 122
    cDNA 121
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924395
References
more
  • Summaries
    All 64
    Gene Ontology 5
    Phenotypes 38
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:266142 Grosjean F, et al., Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice. PLoS One. 2018;13(9):e0204366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/15/2019
MGI 6.13
The Jackson Laboratory