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Nipsnap1
Gene Detail
 Symbol
Name
ID
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
MGI:1278344
Feature Type protein coding gene
Genetic Map
Chromosome 11
3.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:4873951-4894200 bp, + strand
From VEGA annotation of GRCm38

  20250 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2695  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Nipsnap1

Human
homologs
Human Homolog NIPSNAP1, nipsnap homolog 1 (C. elegans)
NCBI Gene ID 8508
neXtProt AC  NX_Q9BPW8
Human Chr (Location)  22q12.2; chr22:29554808-29581337 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(31) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele treated with nocistatin fail to exhibit suppression of neuropeptide nociceptin/orphanin FQ-induced tactile allodynia.
 
Interactions
Nipsnap1 interacts with 186 markers (Mir1a-1, Mir1a-2, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process sensory perception of pain
Component membrane, mitochondrial inner membrane, ...
Function neurotransmitter binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (164)    Tissues (26)    Images (22)
Theiler Stages: 15, 19, 22, 23
Assay TypeResults
RNA in situ 164
cDNA source data(90)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(90) cDNA(90)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005074 (Evidence)
Ensembl Gene ModelENSMUSG00000034285 (Evidence)
Entrez Gene18082 (Evidence)
UniGene293716
DFCITC1574720
DoTSDT.101351178, DT.87073833
NIA Mouse Gene IndexU012276
Consensus CDS ProjectCCDS24392.1
International Mouse Knockout Project StatusNipsnap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005074 VEGA Gene Model | MGI Sequence Detail 20250 C57BL/6J ±  kb
transcript OTTMUST00000011320 VEGA | MGI Sequence Detail 1926 Not Applicable 
polypeptide OTTMUSP00000005277 VEGA | MGI Sequence Detail 284 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(8) UniProt(5)
Polymorphisms SNPs within 2kb(166 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011008 Dimeric alpha-beta barrel
InterPro IPR012577 NIPSNAP
Protein Ontology PR:000011220 protein NipSnap homolog 1
References (Earliest) J:48071 Seroussi E, et al., Characterization of the human NIPSNAP1 gene from 22q12: a member of a novel gene family. Gene. 1998 May 28;212(1):13-20
(Latest) J:183272 Okuda-Ashitaka E, et al., Identification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmission. J Biol Chem. 2012 Mar 23;287(13):10403-13
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory