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Rpl21 Gene Detail
Summary
  • Symbol
    Rpl21
  • Name
    ribosomal protein L21
  • Synonyms
    8430440E03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1278340
    NCBI Gene: 19933
  • Gene Overview
    MyGene.info: RPL21
Location & Maps
more
  • Sequence Map
    Chr5:146832890-146837032 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4143 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 86.50 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    RPL21, ribosomal protein L21
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RPL21, ribosomal protein L21
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HYPT12, L21
  • Links
    NCBI Gene ID: 6144
    neXtProt AC: NX_P46778

  • Chr Location
    13q12.2; chr13:27251555-27256568 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human RPL21 associations

Human Disease Mouse Models
       Hypotrichosis 12; HYPT12   OMIM: 615885
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    31
  • Gene trapped
    29
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024591 VEGA Gene Model | MGI Sequence Detail 4143 C57BL/6J ±  kb
transcript OTTMUST00000060417 VEGA | MGI Sequence Detail 899 Not Applicable  
polypeptide OTTMUSP00000029469 VEGA | MGI Sequence Detail 160 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    88 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000014200 60S ribosomal protein L21
  • InterPro Domains
    IPR001147 Ribosomal protein L21e
    IPR018259 Ribosomal protein L21e, conserved site
    IPR008991 Translation protein SH3-like domain
Molecular
Reagents
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  • All nucleic 13
    Genomic 2
    cDNA 11

    Microarray probesets 12
Other
Accession IDs
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MGI:1914064
References
more
  • Summaries
    All 37
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:213754 Plaks V, et al., Blastocyst implantation failure relates to impaired translational machinery gene expression. Reproduction. 2014 Jul;148(1):87-98

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory