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Rpl21 Gene Detail
Summary
  • Symbol
    Rpl21
  • Name
    ribosomal protein L21
  • Synonyms
    8430440E03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1278340
    NCBI Gene: 19933
  • Gene Overview
    MyGene.info: RPL21
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:146832890-146837032 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 86.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1278340
protein coding gene Chr5:146832890-146837032 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030379
protein coding gene Chr5:152443840-152447985 (+)
A/J MGP_AJ_G0030352
protein coding gene Chr5:145992910-145997074 (+)
AKR/J MGP_AKRJ_G0030279
protein coding gene Chr5:150479276-150483438 (+)
BALB/cJ MGP_BALBcJ_G0030361
protein coding gene Chr5:147206204-147210368 (+)
C3H/HeJ MGP_C3HHeJ_G0030075
protein coding gene Chr5:151413913-151419187 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030816
protein coding gene Chr5:158014373-158018515 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028029
protein coding gene Chr5:140407321-140411319 (+)
CAST/EiJ MGP_CASTEiJ_G0029477
protein coding gene Chr5:150980186-150984348 (+)
CBA/J MGP_CBAJ_G0030053
protein coding gene Chr5:164603740-164610964 (+)
DBA/2J MGP_DBA2J_G0030197
protein coding gene Chr5:145675291-145680838 (+)
FVB/NJ MGP_FVBNJ_G0030151
protein coding gene Chr5:144864918-144869060 (+)
LP/J MGP_LPJ_G0030284
protein coding gene Chr5:153137943-153142088 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030187
protein coding gene Chr5:166913533-166918203 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030846
protein coding gene Chr5:150377358-150381520 (+)
PWK/PhJ MGP_PWKPhJ_G0029191
protein coding gene Chr5:144744250-144748727 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029027
protein coding gene Chr5:147676201-147678994 (+)
WSB/EiJ MGP_WSBEiJ_G0029554
protein coding gene Chr5:151169273-151173420 (+)



Homology
more
  • Human Ortholog
    RPL21, ribosomal protein L21
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RPL21, ribosomal protein L21
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HYPT12, L21
  • Links
    NCBI Gene ID: 6144
    neXtProt AC: NX_P46778
    UniProt: P46778

  • Chr Location
    13q12.2; chr13:27251555-27256568 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human RPL21 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19933 NCBI Gene Model | MGI Sequence Detail 4143 C57BL/6J ±  kb
transcript NM_019647 RefSeq | MGI Sequence Detail 1871 C57BL/6  
polypeptide O09167 UniProt | EBI | MGI Sequence Detail 160 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001147 Ribosomal protein L21e
    IPR018259 Ribosomal protein L21e, conserved site
    IPR036948 Ribosomal protein L21 superfamily
    IPR008991 Translation protein SH3-like domain superfamily
Molecular
Reagents
less
  • All nucleic 14
    Genomic 2
    cDNA 12

    Microarray probesets 12
Other
Accession IDs
less
MGI:1914064
References
more
  • Summaries
    All 38
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:239387 Stafford DA, et al., Deletion of the sclerotome-enriched lncRNA PEAT augments ribosomal protein expression. Proc Natl Acad Sci U S A. 2017 Jan 03;114(1):101-106

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory