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Epc2
Gene Detail
Symbol

Name
ID
Epc2
enhancer of polycomb homolog 2 (Drosophila)
MGI:1278321
Synonyms
D2Ertd694e
Feature Type
protein coding gene
Genetic Map
Chromosome 2
28.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:49451486-49551948 bp, + strand
From VEGA annotation of GRCm38

  100463 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32274  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: EPC2
Gene Tree: Epc2

Human
homologs
EPC2, enhancer of polycomb homolog 2 (Drosophila)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 26122
neXtProt AC: NX_Q52LR7

Human Synonyms: EPC-LIKE

Human Chr (Location): 2q23.1; chr2:148644811-148788491 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(43) : Gene trapped(40) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Epc2 interacts with 414 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cellular response to DNA damage stimulus, chromatin modification, ...
Component NuA4 histone acetyltransferase complex, nucleus, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(81)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase epc2 ; ZFIN epc2    NEW 
Molecular
reagents
All nucleic(82) cDNA(81) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000012480 (Evidence)
Ensembl Gene Model ENSMUSG00000069495 (Evidence)
Entrez Gene 227867 (Evidence)
UniGene 29167
DFCI TC1578493, TC1652218
DoTS DT.531581
NIA Mouse Gene Index U001742
Consensus CDS Project CCDS16023.1
International Mouse Phenotyping Consortium Status Epc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012480 VEGA Gene Model | MGI Sequence Detail 100463 C57BL/6J ±  kb
transcript OTTMUST00000029659 VEGA | MGI Sequence Detail 4697 Not Applicable 
polypeptide OTTMUSP00000013338 VEGA | MGI Sequence Detail 808 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(307 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009607 Enhancer of polycomb, C-terminal
InterPro IPR019542 Enhancer of polycomb-like, N-terminal
InterPro IPR024943 Enhancer of polycomb protein
Protein Ontology PR:000007117 enhancer of polycomb homolog 2
References
(Earliest) J:43737 Stankunas K, et al., The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals. Development. 1998 Oct;125(20):4055-66
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:1277221

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory