Fpr2
Gene Detail

Symbol Name ID

Fpr2 formyl peptide receptor 2 MGI:1278319

Synonyms

E330010I07Rik, Fpr-rs2

Feature Type

protein coding gene

Genetic Map

Chromosome 17

10.66 cM, cytoband A3.1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr17:17887824-17893952 bp, + strand From VEGA annotation of GRCm38   6129 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:74395  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog

Gene Tree: Fpr2

Human homologs

Human Homolog		FPR2, formyl peptide receptor 2
NCBI Gene ID		2358
neXtProt AC		NX_P25090
Human Synonyms		ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
Human Chr (Location)		19q13.3-q13.4; chr19:52264453-52273779 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(7) : Targeted(7)
 

Mice homozygous for a targeted reporter allele exhibit altered leukocyte responses and experimentally induced inflammation.

 

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	chemotaxis, G-protein coupled receptor signaling pathway, ...
Component	integral to membrane, membrane, ...
Function	G-protein coupled receptor activity, N-formyl peptide receptor activity, ...

External Resources: FuncBase

Expression

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(11) Genomic(7) cDNA(4)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000021056 (Evidence)
Ensembl Gene Model	ENSMUSG00000052270 (Evidence)
Entrez Gene	14289 (Evidence)
UniGene	485634
DFCI	TC1617545, TC1754878
DoTS	DT.91328849, DT.91586700
Consensus CDS Project	CCDS28419.1
International Mouse Knockout Project Status	Fpr2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021056	VEGA Gene Model | MGI Sequence Detail	6129	C57BL/6J
transcript	OTTMUST00000049809	VEGA | MGI Sequence Detail	1133	Not Applicable
polypeptide	OTTMUSP00000023136	VEGA | MGI Sequence Detail	351	Not Applicable

All sequences(20) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(39 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000826	Formyl/methionyl peptide receptor
InterPro	IPR000276	GPCR, rhodopsin-like
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM

References

(Earliest) J:49567 Gao JL, et al., Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse. Genomics. 1998 Jul 15;51(2):270-6
(Latest) J:194112 Liu Y, et al., Cell surface receptor FPR2 promotes antitumor host defense by limiting M2 polarization of macrophages. Cancer Res. 2013 Jan 15;73(2):550-60
All references(41)

Other accession IDs

MGI:2442028