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Fpr2
Gene Detail
 Symbol
Name
ID
Fpr2
formyl peptide receptor 2
MGI:1278319
Synonyms E330010I07Rik, Fpr-rs2
Feature Type protein coding gene
Genetic Map
Chromosome 17
10.66 cM, cytoband A3.1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:17887824-17893952 bp, + strand
From VEGA annotation of GRCm38

  6129 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74395  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Fpr2

Human
homologs
Human Homolog FPR2, formyl peptide receptor 2
NCBI Gene ID 2358
neXtProt AC  NX_P25090
Human Synonyms  ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
Human Chr (Location)  19q13.3-q13.4; chr19:51760925-51770526 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Targeted(8)
Incidental mutations (data from APF )
 
Mice homozygous for a targeted reporter allele exhibit altered leukocyte responses and experimentally induced inflammation.
 
Interactions
Fpr2 interacts with 16 markers (Mir1a-1, Mir1a-2, Mir146, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process chemotaxis, G-protein coupled receptor signaling pathway, ...
Component integral component of membrane, membrane, ...
Function G-protein coupled receptor activity, N-formyl peptide receptor activity, ...
External Resources: FuncBase
Expression
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) Genomic(7) cDNA(3)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000021056 (Evidence)
Ensembl Gene ModelENSMUSG00000052270 (Evidence)
Entrez Gene14289 (Evidence)
DFCITC1617545, TC1754878
DoTSDT.91328849, DT.91586700
Consensus CDS ProjectCCDS28419.1
International Mouse Knockout Project StatusFpr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021056 VEGA Gene Model | MGI Sequence Detail 6129 C57BL/6J ±  kb
transcript OTTMUST00000049809 VEGA | MGI Sequence Detail 1133 Not Applicable 
polypeptide OTTMUSP00000023136 VEGA | MGI Sequence Detail 351 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(49 from dbSNP Build 137)    SNPs within 2kb including multiple locations(53)
Protein-related
information
ResourceIDDescription
InterPro IPR000826 Formyl peptide receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
References (Earliest) J:49567 Gao JL, et al., Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse. Genomics. 1998 Jul 15;51(2):270-6
(Latest) J:204838 Dalli J, et al., Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor. J Immunol. 2013 Jun 15;190(12):6478-87
All references(48)
Other
accession IDs
MGI:2442028

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory