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Sap18 Gene Detail
Summary
  • Symbol
    Sap18
  • Name
    Sin3-associated polypeptide 18
  • Synonyms
    C530046K05Rik, D11Ertd539e, EMegR4, Sap18a, Sinbp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277978
    NCBI Gene: 20220
  • Gene Overview
    MyGene.info: SAP18
Location & Maps
more
  • Sequence Map
    Chr14:57798180-57804980 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6801 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 30.51 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SAP18, Sin3A associated protein 18
  • Vertebrate Orthologs
    12
  • Human Ortholog
    SAP18, Sin3A associated protein 18
    Orthology source: HGNC, HomoloGene
  • Synonyms
    2HOR0202, SAP18P
  • Links
    NCBI Gene ID: 10284
    neXtProt AC: NX_O00422

  • Chr Location
    13q12.11; chr13:21140514-21149085 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Sap18
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022377 VEGA Gene Model | MGI Sequence Detail 6801 C57BL/6J ±  kb
transcript OTTMUST00000053448 VEGA | MGI Sequence Detail 3467 Not Applicable  
polypeptide OTTMUSP00000025412 VEGA | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    28 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 25
    cDNA 24
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1203397, MGI:1261774, MGI:2443909
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:46097 Boehmelt G, et al., Cloning of the murine transcriptional corepressor component SAP18 and differential expression of its mRNA in the hematopoietic hierarchy. Gene. 1998 Jan 30;207(2):267-75
  • Latest
    J:156017 Yokoyama S, et al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory