About   Help   FAQ
Sap18 Gene Detail
Summary
  • Symbol
    Sap18
  • Name
    Sin3-associated polypeptide 18
  • Synonyms
    C530046K05Rik, D11Ertd539e, EMegR4, Sap18a, Sinbp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277978
    NCBI Gene: 20220
  • Gene Overview
    MyGene.info: SAP18
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:57798189-57804980 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 30.51 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277978
protein coding gene Chr14:57798180-57806638 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021411
protein coding gene Chr14:52016487-52023287 (+)
A/J MGP_AJ_G0021372
protein coding gene Chr14:50968580-50975380 (+)
AKR/J MGP_AKRJ_G0021347
protein coding gene Chr14:52762586-52769591 (+)
BALB/cJ MGP_BALBcJ_G0021375
protein coding gene Chr14:50910797-50919118 (+)
C3H/HeJ MGP_C3HHeJ_G0021154
protein coding gene Chr14:52415816-52422799 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021814
protein coding gene Chr14:54567386-54575522 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019354
protein coding gene Chr14:49053520-49060228 (+)
CAST/EiJ MGP_CASTEiJ_G0020672
protein coding gene Chr14:48758633-48765415 (+)
CBA/J MGP_CBAJ_G0021121
protein coding gene Chr14:56195092-56201892 (+)
DBA/2J MGP_DBA2J_G0021242
protein coding gene Chr14:50642975-50650282 (+)
FVB/NJ MGP_FVBNJ_G0021223
protein coding gene Chr14:50035114-50043271 (+)
LP/J MGP_LPJ_G0021317
protein coding gene Chr14:53050582-53057889 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021251
protein coding gene Chr14:55531792-55538884 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021838
protein coding gene Chr14:51907572-51914372 (+)
PWK/PhJ MGP_PWKPhJ_G0020415
protein coding gene Chr14:47188863-47195784 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020248
protein coding gene Chr14:47991128-47997906 (+)
WSB/EiJ MGP_WSBEiJ_G0020724
protein coding gene Chr14:52226709-52233509 (+)



Homology
more
  • Human Ortholog
    SAP18, Sin3A associated protein 18
  • Vertebrate Orthologs
    12
  • Human Ortholog
    SAP18, Sin3A associated protein 18
    Orthology source: HomoloGene, HGNC
  • Synonyms
    2HOR0202, SAP18P
  • Links
    NCBI Gene ID: 10284
    neXtProt AC: NX_O00422
    UniProt: O00422

  • Chr Location
    13q12.11; chr13:21140514-21149085 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Sap18
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20220 NCBI Gene Model | MGI Sequence Detail 6792 C57BL/6J ±  kb
transcript NM_009119 RefSeq | MGI Sequence Detail 3472 C57BL/6  
polypeptide O55128 UniProt | EBI | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 26
    cDNA 25
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1203397, MGI:1261774, MGI:2443909
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:46097 Boehmelt G, et al., Cloning of the murine transcriptional corepressor component SAP18 and differential expression of its mRNA in the hematopoietic hierarchy. Gene. 1998 Jan 30;207(2):267-75
  • Latest
    J:156017 Yokoyama S, et al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory