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Zfp143
Gene Detail
Symbol

Name
ID
Zfp143
zinc finger protein 143
MGI:1277969
Synonyms
D7Ertd805e, KRAB14, pHZ-1, Staf, Zfp79, Zfp80-rs1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
57.70 cM, cytoband E3-F1
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr7:110061702-110095392 bp, + strand
From Ensembl annotation of GRCm38

  33691 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56444  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zfp143

Human
homologs
Human Homolog ZNF143, zinc finger protein 143
NCBI Gene ID 7702
neXtProt AC  NX_P52747
Human Synonyms  pHZ-1, SBF, STAF
Human Chr (Location)  11p15.4; chr11:9460965-9528524 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(87) : Gene trapped(85) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous disruption of this locus results in fertility defects.
 
Interactions
Zfp143 interacts with 236 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (54)    Tissues (53)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 46
RT-PCR 8
cDNA source data(58)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(64) Genomic(1) cDNA(59) Primer pair(3) Other(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000061079 (Evidence)
Entrez Gene20841 (Evidence)
UniGene10815
DFCITC1620083, TC1594093, TC1578681
Consensus CDS ProjectCCDS57580.1
International Mouse Knockout Project StatusZfp143
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061079 Ensembl Gene Model | MGI Sequence Detail 33691 C57BL/6J ±  kb
transcript ENSMUST00000084727 Ensembl | MGI Sequence Detail 3013 Not Applicable 
polypeptide ENSMUSP00000081778 Ensembl | MGI Sequence Detail 637 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(8) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(380 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017716 zinc finger protein 143
References
(Earliest) J:29678 Bellefroid EJ, et al., Emergence of the ZNF91 Kruppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea. Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10757-61
(Latest) J:200454 Ngondo-Mbongo RP, et al., Modulation of gene expression via overlapping binding sites exerted by ZNF143, Notch1 and THAP11. Nucleic Acids Res. 2013 Apr;41(7):4000-14
All references(49)
Other
accession IDs
MGD-MRK-36359, MGI:107782, MGI:1289198, MGI:2141851, MGI:2142118

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory