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Bsn
Gene Detail
 Symbol
Name
ID
Bsn
bassoon
MGI:1277955
Synonyms presynaptic cytomatrix protein
Feature Type protein coding gene
Genetic Map
Chromosome 9
59.07 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:108096022-108190384 bp, - strand
From VEGA annotation of GRCm38

  94363 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31161  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Bsn

Human
homologs
Human Homolog BSN, bassoon presynaptic cytomatrix protein
NCBI Gene ID 8927
neXtProt AC  NX_Q9UPA5
Human Synonyms  ZNF231
Human Chr (Location)  3p21.31; chr3:49554489-49671551 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(10) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mutants lacking functional protein exhibit impaired hippocampal and photoreceptor synaptic transmission, aberrant photoreceptor ribbon synapse formation, and spontaneous epileptic seizures.
 
Interactions
Bsn interacts with 446 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Component axon, cell junction, ...
Function metal ion binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (75)    Tissues (37)    Images (45)
Theiler Stages: 19, 23, 24, 26, 28
Assay TypeResults
RNA in situ 75
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) Genomic(2) cDNA(8)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000016899 (Evidence)
Ensembl Gene ModelENSMUSG00000032589 (Evidence)
Entrez Gene12217 (Evidence)
Consensus CDS ProjectCCDS23517.1
International Mouse Knockout Project StatusBsn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016899 VEGA Gene Model | MGI Sequence Detail 94363 C57BL/6J ±  kb
transcript OTTMUST00000041006 VEGA | MGI Sequence Detail 15938 Not Applicable 
polypeptide OTTMUSP00000018359 VEGA | MGI Sequence Detail 3942 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(4) UniProt(4)
Polymorphisms SNPs within 2kb(408 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR008899 Zinc finger, piccolo-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000004830 protein bassoon
References (Earliest) J:48938 Dieck S, et al., Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals. J Cell Biol. 1998 Jul 27;142(2):499-509
(Latest) J:208049 Mendoza Schulz A, et al., Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse. EMBO J. 2014 Mar 3;33(5):512-27
All references(76)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory