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Serpinb3c
Gene Detail
 Symbol
Name
ID
Serpinb3c
serine (or cysteine) peptidase inhibitor, clade B, member 3C
MGI:1277952
Synonyms 1110001H02Rik, 1110013A16Rik, ovalbumin, Scca2, Serpinb4
Feature Type protein coding gene
Genetic Map
Chromosome 1
50.34 cM, cytoband E1-E2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:107271201-107278371 bp, - strand
From VEGA annotation of GRCm38

  7171 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:131278  Vertebrate Homology Class
2 mouse

Protein SuperFamily: serpin
Gene Tree: Serpinb3c

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpinb3c interacts with 78 markers (Mir23a, Mir23b, Mir29a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process negative regulation of endopeptidase activity, regulation of proteolysis
Component extracellular region
Function protein binding, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (20)    Tissues (14)   
Theiler Stages: 28
Assay TypeResults
Northern blot 8
RT-PCR 12
cDNA source data(4)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(20) Genomic(14) cDNA(5) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000021005 (Evidence)
Ensembl Gene ModelENSMUSG00000073601 (Evidence)
Entrez Gene381286 (Evidence)
UniGene337362
DFCITC1591158
DoTSDT.102555919
NIA Mouse Gene IndexU021667
Consensus CDS ProjectCCDS35685.1
International Mouse Knockout Project StatusSerpinb3c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021005 VEGA Gene Model | MGI Sequence Detail 7171 C57BL/6J ±  kb
transcript OTTMUST00000049658 VEGA | MGI Sequence Detail 1659 Not Applicable 
polypeptide OTTMUSP00000023044 VEGA | MGI Sequence Detail 386 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(47 from dbSNP Build 137)    SNPs within 2kb including multiple locations(55)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
References (Earliest) J:49294 Bartuski AJ, et al., A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases. Genomics. 1998 Dec 1;54(2):297-306
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)
Other
accession IDs
MGI:2447807, MGI:2447808

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory