Serpinb3c
Gene Detail

Symbol Name ID

Serpinb3c serine (or cysteine) peptidase inhibitor, clade B, member 3C MGI:1277952

Synonyms

1110001H02Rik, 1110013A16Rik, ovalbumin, Scca2, Serpinb4

Feature Type

protein coding gene

Genetic Map

Chromosome 1

50.34 cM, cytoband E1-E2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr1:107271201-107278371 bp, - strand From VEGA annotation of GRCm38   7171 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:131278  Vertebrate Homology Class
2 mouse

Protein SuperFamily: serpin
Gene Tree: Serpinb3c

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	negative regulation of endopeptidase activity, regulation of proteolysis
Component	extracellular region
Function	protein binding, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (20)    Tissues (14)   
Theiler Stages: 28

Assay Type	Results
Northern blot	8
RT-PCR	12

cDNA source data(4)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(20) Genomic(14) cDNA(5) Primer pair(1)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000021005 (Evidence)
Ensembl Gene Model	ENSMUSG00000073601 (Evidence)
Entrez Gene	381286 (Evidence)
UniGene	337362
DFCI	TC1591158
DoTS	DT.102555919
NIA Mouse Gene Index	U021667
Consensus CDS Project	CCDS35685.1
International Mouse Knockout Project Status	Serpinb3c

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021005	VEGA Gene Model | MGI Sequence Detail	7171	C57BL/6J
transcript	OTTMUST00000049658	VEGA | MGI Sequence Detail	1659	Not Applicable
polypeptide	OTTMUSP00000023044	VEGA | MGI Sequence Detail	386	Not Applicable

All sequences(18) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(22 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family

References

(Earliest) J:49294 Bartuski AJ, et al., A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases. Genomics. 1998 Dec 1;54(2):297-306
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)

Other accession IDs

MGI:2447807, MGI:2447808