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Per3 Gene Detail
Summary
  • Symbol
    Per3
  • Name
    period circadian clock 3
  • Synonyms
    2810049O06Rik, mPer3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277134
    NCBI Gene: 18628
  • Gene Overview
    MyGene.info: PER3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:151003652-151044665 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 81.53 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    461 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277134
protein coding gene Chr4:150997018-151044723 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029161
protein coding gene Chr4:155032883-155074225 (-)
A/J MGP_AJ_G0029126
protein coding gene Chr4:148513997-148555267 (-)
AKR/J MGP_AKRJ_G0029074
protein coding gene Chr4:152582699-152623672 (-)
BALB/cJ MGP_BALBcJ_G0029142
protein coding gene Chr4:149008147-149049221 (-)
C3H/HeJ MGP_C3HHeJ_G0028863
protein coding gene Chr4:153151349-153192334 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029591
protein coding gene Chr4:160601477-160644419 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026837
protein coding gene Chr4:140895155-140936433 (-)
CAST/EiJ MGP_CASTEiJ_G0028276
protein coding gene Chr4:150431192-150473397 (-)
CBA/J MGP_CBAJ_G0028825
protein coding gene Chr4:165367640-165413167 (-)
DBA/2J MGP_DBA2J_G0028974
protein coding gene Chr4:148591291-148632179 (-)
FVB/NJ MGP_FVBNJ_G0028938
protein coding gene Chr4:147734958-147777009 (-)
LP/J MGP_LPJ_G0029064
protein coding gene Chr4:154965924-155006774 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028965
protein coding gene Chr4:168484468-168525460 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029623
protein coding gene Chr4:153110102-153151110 (-)
PWK/PhJ MGP_PWKPhJ_G0027996
protein coding gene Chr4:144627370-144668715 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027830
protein coding gene Chr4:147358110-147399088 (-)
WSB/EiJ MGP_WSBEiJ_G0028356
protein coding gene Chr4:153241835-153285554 (-)



Homology
more
  • Human Ortholog
    PER3, period circadian regulator 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PER3, period circadian regulator 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FASPS3, GIG13
  • Links
    NCBI Gene ID: 8863
    neXtProt AC: NX_P56645
    UniProt: P56645

  • Chr Location
    1p36.23; chr1:7784285-7845181 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7886
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PER3
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human PER3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    10 phenotypes from multigenic genotypes
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation exhibit a shorter circadian cycle length.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028957 Ensembl Gene Model | MGI Sequence Detail 41014 C57BL/6J ±  kb
transcript ENSMUST00000103204 Ensembl | MGI Sequence Detail 5999 Not Applicable  
polypeptide ENSMUSP00000099493 Ensembl | MGI Sequence Detail 1113 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 48
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1919967
References
more
  • Summaries
    All 73
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 24
  • Earliest
    J:44820 Albrecht U, et al., A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell. 1997 Dec 26;91(7):1055-64
  • Latest
    J:256785 Aryal RP, et al., Macromolecular Assemblies of the Mammalian Circadian Clock. Mol Cell. 2017 Sep 7;67(5):770-782.e6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory