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Ptgfrn
Gene Detail
 Symbol
Name
ID
Ptgfrn
prostaglandin F2 receptor negative regulator
MGI:1277114
Synonyms 4833445A08Rik, CD9P-1
Feature Type protein coding gene
Genetic Map
Chromosome 3
43.93 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:101040232-101110278 bp, - strand
From VEGA annotation of GRCm38

  70047 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7908  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: prostaglandin F2 receptor negative regulator
Gene Tree: Ptgfrn

Human
homologs
Human Homolog PTGFRN, prostaglandin F2 receptor inhibitor
NCBI Gene ID 5738
neXtProt AC  NX_Q9P2B2
Human Synonyms  CD315, CD9P-1, EWI-F, FPRP, SMAP-6
Human Chr (Location)  1p13.1; chr1:116910067-116990350 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(30) : Gene trapped(28) Targeted(2)
Incidental mutations (data from APF )
 
Homozygous mice for a null gene trap mutation exhibit a decreased depressive-like response during tail suspension testing when compared with their wild-type littermates,
 
Interactions
Ptgfrn interacts with 387 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process lipid particle organization
Component endoplasmic reticulum, Golgi apparatus, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (139)    Tissues (18)    Images (23)
Theiler Stages: 23
Assay TypeResults
RNA in situ 139
cDNA source data(57)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(58) cDNA(58)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000007094 (Evidence)
Ensembl Gene ModelENSMUSG00000027864 (Evidence)
Entrez Gene19221 (Evidence)
UniGene24807
DFCITC1588809, TC1599507, TC1687125
DoTSDT.101338638, DT.484601, DT.97364955
Consensus CDS ProjectCCDS17680.1
International Mouse Knockout Project StatusPtgfrn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007094 VEGA Gene Model | MGI Sequence Detail 70047 C57BL/6J ±  kb
transcript OTTMUST00000016396 VEGA | MGI Sequence Detail 5902 Not Applicable 
polypeptide OTTMUSP00000007506 VEGA | MGI Sequence Detail 879 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(543 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR003596 Immunoglobulin V-set, subgroup
Protein Ontology PR:000001920 prostaglandin F2 receptor negative regulator
References (Earliest) J:48066 Orlicky DJ, et al., Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells. J Lipid Res. 1998 Jun;39(6):1152-61
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2139911

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory