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Ankrd22 Gene Detail
Summary
  • Symbol
    Ankrd22
  • Name
    ankyrin repeat domain 22
  • Synonyms
    5430429D21Rik, D19Ertd675e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277101
    NCBI Gene: 52024
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:34099949-34143441 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 29.33 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    998 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277101
 protein coding gene Chr19:34098869-34143453 (-)
129S1/SvImJ ENSMUSG00200029964
 protein coding gene Chr19:30818651-30863234 (-)
A/J ENSMUSG00195010117
 protein coding gene Chr19:30986072-31030662 (-)
AKR/J ENSMUSG00220017433
 protein coding gene Chr19:30881517-30926098 (-)
BALB/cJ ENSMUSG00180027382
 protein coding gene Chr19:31314917-31359502 (-)
C3H/HeJ ENSMUSG00175041164
 protein coding gene Chr19:30710895-30755479 (-)
C57BL/6NJ ENSMUSG00215027670
 protein coding gene Chr19:30737586-30782178 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022886
 protein coding gene Chr19:30709820-30741618 (-)
CAST/EiJ ENSTCUG00005015189
 protein coding gene Chr19:30376553-30410240 (-)
CBA/J ENSMUSG00210029362
 protein coding gene Chr19:30763924-30808512 (-)
DBA/2J ENSMUSG00185030756
 protein coding gene Chr19:31319202-31363780 (-)
FVB/NJ ENSMUSG00205006339
 protein coding gene Chr19:30572304-30603674 (-)
JF1/MsJ ENSUMUG00000044969
 protein coding gene Chr19:31500690-31534405 (-)
LP/J ENSMUSG00230030033
 protein coding gene Chr19:32106048-32150630 (-)
NOD/ShiLtJ ENSMUSG00190009835
 protein coding gene Chr19:30689134-30733721 (-)
NZO/HlLtJ ENSMUSG00225029246
 protein coding gene Chr19:35704390-35742582 (-)
PWK/PhJ ENSLUMG00010001241
 protein coding gene Chr19:30866914-30900543 (-)
SPRET/EiJ ENSMSPG00010018157
 protein coding gene Chr19:30506367-30537330 (-)
WSB/EiJ ENSIUOG00005038161
 protein coding gene Chr19:30232165-30270317 (-)



Homology
more
  • Human Ortholog
    ANKRD22, ankyrin repeat domain 22
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD22, ankyrin repeat domain 22
  • Links
    NCBI Gene ID: 118932
    UniProt: Q5VYY1

  • Chr Location
    10q23.31; chr10:88819896-88851844 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • Tissues
    32
  • cDNA Data
    11
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52024 NCBI Gene Model | MGI Sequence Detail 43493 C57BL/6J ±  kb
transcript NM_024204 RefSeq | MGI Sequence Detail 1754 ZRU/MplStud  
polypeptide Q9D3J5 UniProt | EBI | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1914809
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:389256 Xia X, et al., ANKRD22 promotes resolution of psoriasiform skin inflammation by antagonizing NIK-mediated IL-23 production. Mol Ther. 2024 May 1;32(5):1561-1577
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory